1416427-50-3Relevant articles and documents
Enantioselective Michael addition of aldehydes to maleimides organocatalysed by chiral 1,2-diamines: An experimental and theoretical study
Avila, Angel,Chinchilla, Rafael,Gomez-Bengoa, Enrique,Najera, Carmen
, p. 1531 - 1535 (2013)
Simple and commercially available chiral 1,2-diamines were used as organocatalysts for the enantioselective conjugate addition of aldehydes, including α,α-disubstituted, to maleimides. The reaction was carried out in the presence of hexanedioic acid as an
Enantioselective Michael addition of α,α-disubstituted aldehydes to maleimides organocatalyzed by chiral primary amine-guanidines
Avila, Angel,Chinchilla, Rafael,Nájera, Carmen
, p. 1625 - 1627 (2013/02/22)
New primary amine-guanidines derived from the monoguanylation of (1S,2S)- and (1R,2R)-cyclohexane-1,2-diamine have been prepared and used as chiral organocatalysts for the enantioselective conjugate addition of α,α-disubstituted aldehydes to maleimides. T