141743-16-0 Usage
Description
FMOC-N-(TERT-BUTYLOXYCARBONYLMETHYL)-GLYCINE, commonly known as Fmoc-N-Boc-Glycine, is a synthetic compound that serves as a crucial intermediate in the field of organic chemistry and pharmaceuticals. It is characterized by its white crystalline powder form and is widely utilized in the synthesis of various protected aminoalkyland carboxyalkylamino acids.
Uses
Used in Pharmaceutical Industry:
FMOC-N-(TERT-BUTYLOXYCARBONYLMETHYL)-GLYCINE is used as a synthetic intermediate for the preparation of protected aminoalkyland carboxyalkylamino acids. These protected amino acids are essential building blocks in the development of various pharmaceutical compounds, including peptides, proteins, and other bioactive molecules. The protection of these amino acids is crucial to prevent unwanted side reactions during the synthesis process, ensuring the desired product is obtained with high purity and yield.
Used in Chemical Research:
In the field of chemical research, FMOC-N-(TERT-BUTYLOXYCARBONYLMETHYL)-GLYCINE is employed as a valuable reagent for the synthesis of complex organic molecules. Its unique structure allows for the exploration of novel chemical reactions and the development of innovative synthetic routes, contributing to the advancement of chemical science and technology.
Used in Peptide Synthesis:
FMOC-N-(TERT-BUTYLOXYCARBONYLMETHYL)-GLYCINE is used as a key component in the solid-phase peptide synthesis (SPPS) process. This technique is widely employed in the production of peptides and proteins, which have numerous applications in the pharmaceutical, biotechnological, and medical industries. The use of Fmoc-N-Boc-Glycine in SPPS enables the efficient and controlled assembly of peptide chains, leading to the synthesis of high-quality and well-defined peptide products.
Check Digit Verification of cas no
The CAS Registry Mumber 141743-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,7,4 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 141743-16:
(8*1)+(7*4)+(6*1)+(5*7)+(4*4)+(3*3)+(2*1)+(1*6)=110
110 % 10 = 0
So 141743-16-0 is a valid CAS Registry Number.
141743-16-0Relevant articles and documents
Design, synthesis, and hybridisation of water-soluble, peptoid nucleic acid oligomers tagged with thymine
Zarra, Rosa,Montesarchio, Daniela,Coppola, Cinzia,Bifulco, Giuseppe,Di Micco, Simone,Izzo, Irene,De Riccardis, Francesco
experimental part, p. 6113 - 6120 (2010/03/26)
The preparation of a new class of backbone-modified PNA mimetic incorporating thymine is described. Target dipeptoid monomer 21 was synthesised from an N-[2-(thyniin-l-yl)ethyl]glycinate ester and a properly protected iminodiacetic acid. The distinctive s
Building Units for N-Backbone Cyclic Peptides. 3. Synthesis of Protected Nα-(ω-Aminoalkyl)amino Acids and Nα-(ω-Carboxyalkyl)amino Acids
Muller, Dan,Zeltser, Irena,Bitan, Gal,Gilon, Chaim
, p. 411 - 416 (2007/10/03)
An improved synthesis of a family of amino acids that contain ω-aminoalkyl groups and of a new family containing ω-carboxyalkyl groups linked to the α-amine is described. The synthesis was performed by alkylation of suitably monoprotected alkylenediamines and protected ω-amino acids with triflates of α-hydroxy acid esters. The reaction proceeded with inversion of configuration yielding optically pure products. The Nα-(ω-aminoalkyl)amino acids and Nα-(ω-carboxyalkyl)amino acids were orthogonally protected to allow their incorporation into peptides by solid-phase peptide synthesis (SPPS) methodology.
