141754-29-2Relevant academic research and scientific papers
Generation and trapping of electron-deficient 1,2-cyclohexadienes. Unexpected hetero-Diels-Alder reactivity
Wang, Baolei,Constantin, Marius-Georgian,Singh, Simarpreet,Zhou, Yuqiao,Davis, Rebecca L.,West
, p. 399 - 405 (2021)
Keto-substituted 1,2-cyclohexadienes were generated by base-mediated (KOt-Bu) elimination, and found to dimerize via an unprecedented formal hetero-Diels-Alder process, followed by hydration. These highly reactive cyclic allene intermediates were also tra
Nonpeptide angiotensin II receptor antagonists: Synthetic and computational chemistry of N-[[4-[2-(2H-tetrazol-5-yl)-1-cycloalken-1- yl]phenyl]methyl]imidazole derivatives and their in vitro activity
Lin,Rampersaud,Zimmerman,Steinberg,Boyd
, p. 2658 - 2667 (2007/10/02)
A series of nonpeptide angiotensin II receptor antagonists was synthesized and tested in vitro to investigate requirements for recognition by and binding to AT1 receptors. Compared to a known series of N- (biphenylylmethyl)imidazoles, including
