141811-29-2

Usage

Type of Compound

Chemical compound

Usage

Commonly used in medicinal and pharmaceutical research

Derivative of

Bicyclic compound 1,3-benzocyclooctene

Contains

Two carbonitrile groups

Other Component

2-amino-5,6,7,8,9,10-hexahydro-4-phenylis a cyclic amine compound

Contains in cyclic amine

Phenyl group and an amino group

Application

Used in the synthesis of various organic compounds

Interest

Fields of medicinal chemistry and pharmacology

Potential

Applications in drug discovery and development

Reason for potential

Unique chemical structures and properties

Upstream product

• 502-49-8 cycloactanone 
• 100-52-7 benzaldehyde 
• 109-77-3 malononitrile 
• 40106-05-6 cyclooctylidene-malononitrile 
• 709-79-5 2-cyano-3-phenylacrylamide 

Relevant academic research and scientific papers

'On-water' one-pot pseudo four-component domino protocol for the synthesis of novel benzo[a]cyclooctenes

An environmentally benign 'on-water' pseudo four-component, domino protocol for the synthesis of novel benzo[a]cyclooctenes is reported. The reaction presumably occurs via a domino Knoevenagel condensation-Michael addition-Thorpe-Ziegler cyclization-tautomerization-elimination sequence of reactions.

Novel Synthesis of Indans, Tetralones, Condensed Benzocarbocyclic Nitriles and Condensed Pyridine-2(1H)-thiones from the Reactions of Cycloalkylidenemalononitriles with Arylmethylene(cyano)-acetamide and -thioacetamide

A novel synthesis of indans, tetralons, condensed benzocarbocyclic nitriles and condensed pyridine-2(1H)-thiones from cycloalkylidenemalononitrile and arylmethylene(cyano)-acetamide and -thioacetamide is described.