141815-15-8 Usage
Uses
Used in Pharmaceutical Industry:
C-(4-Cyclopropylmethyl-morpholin-2-yl)-methylamine dihydrochloride is used as a building block for the synthesis of various pharmaceuticals due to its unique structural features that can be incorporated into drug molecules to enhance their therapeutic properties and improve their pharmacokinetic profiles.
Used in Agrochemical Industry:
In the agrochemical sector, C-(4-Cyclopropylmethyl-morpholin-2-yl)-methylamine dihydrochloride serves as a key intermediate in the production of agrochemicals, contributing to the development of effective compounds for crop protection and enhancement of agricultural yields.
Used in Fine Chemicals Synthesis:
C-(4-Cyclopropylmethyl-morpholin-2-yl)-methylamine dihydrochloride is utilized as a versatile building block in the synthesis of fine chemicals, where its specific structural attributes can be leveraged to create specialty chemicals for various applications, including but not limited to fragrances, dyes, and other high-value products.
Check Digit Verification of cas no
The CAS Registry Mumber 141815-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,8,1 and 5 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 141815-15:
(8*1)+(7*4)+(6*1)+(5*8)+(4*1)+(3*5)+(2*1)+(1*5)=108
108 % 10 = 8
So 141815-15-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H18N2O.2ClH/c10-5-9-7-11(3-4-12-9)6-8-1-2-8;;/h8-9H,1-7,10H2;2*1H
141815-15-8Relevant academic research and scientific papers
Novel benzamides as selective and potent gastrokinetic agents. III. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]-benzamides
Kato,Morie,Harada,Yoshida,Matsumoto
, p. 652 - 660 (2007/10/02)
A series of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]benzamides (11-44) were prepared and evaluated for gastrokinetic activity by determining their effects on the gastric emptying of phenol red semisolid meal in rats. The N-4 substituent includes alkyl, phenoxyalkyl, (4-fluorobenzoyl)alkyl, and heteroarylmethyl groups. The benzamide derivatives, having an isopropyl, isoamyl, neopentyl, 3-(4-chlorophenoxy)propyl, or pyridylmethyl group at N-4, showed potent in vivo gastric emptying activity. In particular, 4-amino-5-chloro-2-ethoxy-N-[[4-(3-pyridylmethyl)-2-morpholinyl]methyl ]benzamide (57b) was equipotent to the 4-fluorobenzyl analogue 1b (AS-4370 as its citrate) in the gastrokinetic activity on phenol red semisolid meal in rats and mice, and on resin pellet solid meal in rats. Moreover, compound 57b was free from dopamine D2 receptor antagonistic activity in both in vitro ([3H]spiperone binding) and in vivo (apomorphine-induced emesis in dogs) tests. Structure-activity relationships of compounds with various substituents at N-4 are also discussed.
