141855-39-2

Upstream product

• 141855-27-8 2-diethylamino-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 624-90-8 Methanesulfonyl azide 
• 7145-87-1 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one 

Downstream Products

• 141855-58-5 3-diethylamino-4-hydroxy-4-(4-methoxyphenyl)-4,5H-isothiazolin-1,1-dioxide 
• 141855-74-5 4-chloro-3-diethylamino-4-(4-methoxyphenyl)-4,5H-isothiazolin-1,1-dioxide 
• 141855-68-7 4-chloro-3-diethylamino-4-(4-methoxyphenyl)-4,5-dihydroisothiazole-1,1-dioxide 
• 199383-67-0 5-bromo-3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide 
• 222311-17-3 3-diethylamino-4-(4-methoxyphenyl)-5-methylsulfanyl-isothiazole 1,1-dioxide 

Relevant academic research and scientific papers

Synthesis, conformation and antiproliferative activity of isothiazoloisoxazole 1,1-dioxides

Sixteen new isothiazoloisoxazole 1,1-dioxides, one new isothiazolotriazole and one new isothiazolopyrazole have been synthesised by using 1,3-dipolar cycloadditions to isothiazole 1,1-dioxides. One sub-set of these isothiazoloisoxazoles showed low μM acti

N-Sulfonylamidines. Part IV. Intramolecular Cyclization of N-Sulfonylamidines of 2-Oxoacids: a new Synthesis of 3-Aminoisothiazole S,S-dioxides

N-alkylsulfonylamides of α-ketoacids 3 bearing both a carbonyl group and at least one H-atom near to the SO2 group give easily an intramolecular ring-closure reaction by action of potassium t-butoxide producing the 3-amino-4,5-dihydro-4-hydroxy-isothiazol