141855-39-2Relevant academic research and scientific papers
Synthesis, conformation and antiproliferative activity of isothiazoloisoxazole 1,1-dioxides
Blackburn,Molyneux,Pitard,Rice,Page,Afshinjavid,Javid,Coles,Horton,Hemming
supporting information, p. 2134 - 2144 (2016/02/18)
Sixteen new isothiazoloisoxazole 1,1-dioxides, one new isothiazolotriazole and one new isothiazolopyrazole have been synthesised by using 1,3-dipolar cycloadditions to isothiazole 1,1-dioxides. One sub-set of these isothiazoloisoxazoles showed low μM acti
N-Sulfonylamidines. Part IV. Intramolecular Cyclization of N-Sulfonylamidines of 2-Oxoacids: a new Synthesis of 3-Aminoisothiazole S,S-dioxides
Clerici, Francesca,Marazzi, Guiseppe,Taglietti, Marcello
, p. 3227 - 3238 (2007/10/02)
N-alkylsulfonylamides of α-ketoacids 3 bearing both a carbonyl group and at least one H-atom near to the SO2 group give easily an intramolecular ring-closure reaction by action of potassium t-butoxide producing the 3-amino-4,5-dihydro-4-hydroxy-isothiazol
