7145-87-1

Usage

Appearance

Yellow crystalline powder This chemical compound is a yellow-colored solid that forms needle-like or blocky crystals.

Usage in organic synthesis

Precursor for pharmaceuticals and other organic compounds The compound serves as a starting material or intermediate in the synthesis of various pharmaceuticals and other organic compounds, due to its reactive functional groups.

Chemical classification

Ketone derivative 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one is classified as a ketone, which means it contains a carbonyl functional group (C=O) bonded to two carbon atoms within the carbon chain.

Presence of substituents

Two bromine atoms and a phenyl group The presence of two bromine atoms at the 2 and 3 positions and a 4-methoxyphenyl group attached to the carbon chain makes 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one unique and imparts specific reactivity and properties.

Potential applications

Synthesis of new drugs The compound has potential applications in the pharmaceutical industry for the development of new drugs, thanks to its versatile structure and reactivity.

Use as a reagent

Preparation of other organic compounds 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one can also be used as a reagent in chemical reactions for the preparation of other organic compounds, making it a valuable building block in organic chemistry.

Safety precautions

Skin and eye irritation, harmful health effects It is important to handle 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one with care, as it may cause skin and eye irritation, and exposure to high levels of the chemical may result in harmful health effects.

Upstream product

• 959-23-9 4'-methoxychalcone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 
• 22966-19-4 trans-4'-methoxychalcone 
• 100-66-3 methoxybenzene 
• 102-92-1 cinnamoyl chloride 

Downstream Products

• 132971-99-4 (Z)-2-bromo-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 222311-17-3 3-diethylamino-4-(4-methoxyphenyl)-5-methylsulfanyl-isothiazole 1,1-dioxide 
• 199383-67-0 5-bromo-3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide 

Relevant academic research and scientific papers

Dibrominated addition and substitution of alkenes catalyzed by Mn2(CO)10

A practical method for the dibromination of alkenes without using molecular bromine is consistently appealing in organic synthesis. Herein, we report Mn-catalyzed dibrominated addition and substitution of alkenes only with N-bromosuccinimide, producing a variety of synthetically valuable dibrominated compounds in moderate to high yields. This journal is

Modular access to 1,2-allenyl ketones based on a photoredox-catalysed radical-polar crossover process

Herein, a new protocol dealing with the preparation of 1,2-allenyl ketones has been successfully developedviathe reactions of enynes with radicals enabled by dual photoredox/copper catalysis. Based on the results of a deuteration experiment and the competition reaction between cyclopropanation and allenation, the mechanism based on a photoredox-neutral-catalysed radical-polar crossover process has been proposed. Synthetic applications of allenes have also been demonstrated.

I2O5-mediated bromohydroxylation and dibromination of olefins using KBr in water

An efficient and green bromohydroxylation and dibromination of various olefins mediated by I2O5 has been developed in this work. A series of olefins gave the corresponding α-bromo-alcohols and dibromides as the major products using KBr as the brominating reagent in aqueous medium at room temperature. The diastereo- and regio-selectivities are extremely high.

Ecofriendly bromination of chalcones and synthesis of flavones using grinding technique

Selective bromination of chalcones and 2'-hydroxychalcones has been carried out with ammonium bromide and ammonium persulphate using grinding technique at RT under aqueous moist condition to give α,β-dibromochalcones and α,β-dibromo-2'- hydroxychalcones respectively. α,β- Dibromo-2'-hydroxychalcones have been cyclodehydrobrominated with barium hydroxide moist and ethanol at RT to give flavones using grinding technique.

Chemoselective C-C bond cleavage of epoxide motifs: Gold(I)-catalyzed diastereoselective [4+3] cycloadditions of 1-(1-Alkynyl)oxiranyl ketones and nitrones

Cutting carbon! A novel facile strategy for the C-C bond cleavage of oxiranyl ketones has been developed. Carbophilic gold(I) activation of the alkyne side chain mediates a heterocyclization and subsequent C-C bond cleavage (see scheme).