222311-17-3

Upstream product

• 199383-67-0 5-bromo-3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide 
• 5188-07-8 sodium thiomethoxide 
• 141855-74-5 4-chloro-3-diethylamino-4-(4-methoxyphenyl)-4,5H-isothiazolin-1,1-dioxide 
• 141855-27-8 2-diethylamino-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 141855-39-2 N-[1-Diethylamino-2-(4-methoxy-phenyl)-2-oxo-eth-(Z)-ylidene]-methanesulfonamide 
• 7145-87-1 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 141855-58-5 3-diethylamino-4-hydroxy-4-(4-methoxyphenyl)-4,5H-isothiazolin-1,1-dioxide 

Relevant academic research and scientific papers

Synthesis, conformation and antiproliferative activity of isothiazoloisoxazole 1,1-dioxides

Sixteen new isothiazoloisoxazole 1,1-dioxides, one new isothiazolotriazole and one new isothiazolopyrazole have been synthesised by using 1,3-dipolar cycloadditions to isothiazole 1,1-dioxides. One sub-set of these isothiazoloisoxazoles showed low μM acti

Isothiazoles. Part IX. An efficient synthetic route to 5-substituted-3- amino-4-arylisothiazole 1,1-dioxides and their 4,5-dihydro derivatives

A simple method to introduce an heteroatom substituent at C-5 of isothiazole dioxides is reported. Through Michael addition reactin 5- substituted isothiazole and 4,5-dihydroisothiazole 1,1-dioxides were obtained allowing the preparation of a series of derivatives of special interst for biological studies.