141887-86-7

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 141887-87-8 (S)-2,2-Dimethyl-4-((E)-4-phenyl-but-1-enyl)-[1,3]dioxolane 
• 7484-37-9 (3-phenylpropyl)triphenylphosphonium bromide 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 90145-12-3 (S)-6-phenylhexane-1,2-diol 
• 141887-85-6 5-{(1R,2R,3S,5R,6R,7R)-2-Iodo-6-[(E)-(S)-7-phenyl-3-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-hept-1-enyl]-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl}-pentanoic acid methyl ester 
• 141887-87-8 2,2-Dimethyl-4-((E)-4-phenyl-but-1-enyl)-[1,3]dioxolane 
• 90145-12-3 6-Phenyl-1,2-hexandiol 

Relevant academic research and scientific papers

An azido-functionalized isocarbacyclin analogue acting as an efficient photoaffinity probe for a prostacyclin receptor

A stable prostacyclin analogue, (15S)-18c, having an azidophenyl group as a photoaffinity labeling functionality has been synthesized. This compound has a sufficiently high affinity to the prostacyclin receptor protein in mastocytoma P-815 cells, exhibiting an IC50 value of 3 nM for the replacement of iloprost bound to the receptor protein. A photoaffinity probe compound, [3H]-(15S)-18c, is obtainable by reduction of the ketone 16c with [3H]NaBH4 - CeCl3 followed by alkaline hydrolysis of the methyl ester.