90145-12-3

Upstream product

• 1588-44-9 6-phenyl-1-hexene 
• 637-59-2 1-Bromo-3-phenylpropane 
• 86088-39-3 2-(5-phenylbutyl)oxirane 
• 36884-28-3 5-phenyl-1-pentanal 
• 141887-87-8 (S)-2,2-Dimethyl-4-((E)-4-phenyl-but-1-enyl)-[1,3]dioxolane 
• 7484-37-9 (3-phenylpropyl)triphenylphosphonium bromide 
• 10521-91-2 5-phenylpentan-1-ol 
• 141887-87-8 2,2-Dimethyl-4-((E)-4-phenyl-but-1-enyl)-[1,3]dioxolane 

Downstream Products

• 1149764-74-8 C₂₆H₂₄N₂O₈ 
• 821785-90-4 (R)-8-phenyloct-1-en-4-ol 
• 397871-03-3 (6R)-6-[(1E,4R,6R)-4,6-dihydroxy-10-phenyldec-1-en-1-yl]-5,6-dihydro-2H-pyran-2-one 
• 934473-37-7 tert-butyl-{4-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-1-[2-(4-methoxy-benzyloxy)-ethyl]-but-2-enyloxy}-dimethyl-silane 
• 934473-35-5 9-(tert-butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-13-phenyl-tridec-4-yne-3,7-diol 
• 934473-25-3 5-(tert-butyl-dimethyl-silanyloxy)-8-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-octa-2,6-dienoic acid methyl ester 
• 934473-36-6 6-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-1-(4-methoxy-benzyloxy)-hex-4-yn-3-ol 
• 934473-26-4 1-(4-methoxy-benzyloxy)-13-phenyl-tridec-4-yne-3,7,9-triol 
• 934473-30-0 6-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-1-(4-methoxy-benzyloxy)-hex-4-en-3-ol 
• 934473-31-1 3-(tert-butyl-dimethyl-silanyloxy)-6-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-hex-4-en-1-ol 
• 1026938-84-0 3-(tert-butyl-dimethyl-silanyloxy)-6-[2,2-dimethyl-6-(4-phenyl-butyl)-[1,3]dioxan-4-yl]-hex-4-enal 
• 934473-34-4 (2R,4R)-4-(tert-butyldimethylsilyloxy)-8-phenyloctane-1,2-diol 
• 934473-27-5 tert-butyl-dimethyl-(1-oxiranylmethyl-5-phenyl-pentyloxy)-silane 
• 934473-29-7 tert-butyl-dimethyl-(1-oxiranylmethyl-5-phenyl-pentyloxy)-silane 

Relevant academic research and scientific papers

Stereoselective synthesis of (6S) and (6R)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and their cytotoxic activity against cancer cell lines

Stereoselective total synthesis of α,β-unsaturated lactone (1a), isolated from Ravensara crassifolia, has been achieved efficiently starting from chiral 2,3-O-isopropylidene-d-glyceraldehyde (3) followed by asymmetric allylation and ring-closing metathesi

First stereoselective total synthesis of (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran- 2-one

A stereoselective total synthesis of (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran- 2-one is reported. The strategy utilizes an iterative Jacobsen hydrolytic kinetic resolution, ring opening with a chiral propargylic synthon and

An azido-functionalized isocarbacyclin analogue acting as an efficient photoaffinity probe for a prostacyclin receptor

A stable prostacyclin analogue, (15S)-18c, having an azidophenyl group as a photoaffinity labeling functionality has been synthesized. This compound has a sufficiently high affinity to the prostacyclin receptor protein in mastocytoma P-815 cells, exhibiting an IC50 value of 3 nM for the replacement of iloprost bound to the receptor protein. A photoaffinity probe compound, [3H]-(15S)-18c, is obtainable by reduction of the ketone 16c with [3H]NaBH4 - CeCl3 followed by alkaline hydrolysis of the methyl ester.

Synthesis and Complex Formation of Phenyl- and (4-Phenylbutyl)-substituted Crown Ethers

A number of phenyl and (4-phenylbutyl) derivates of 18-C-6 and 24-C-8 have been prepared: tetraphenyl-diene-18-crown-6 (TPDE-18-C-6), tetraphenyl-18-crown-6 (TP-18-C-6), tetraphenyldiene-24-crown-8 (TPDE-24-C-8), tetraphenyl-24-crown-8 (TP-24-C-8), and bis(4-phenylbutyl)-18-crown-6 (BPB-18-C-6).The ring formation reactions have been carried out by phase-transfer catalysis.All compounds are solids at room temperature except for the liquid BPB-18-C-6 wich represents a mixture of isomers.The syn- and anti-isomers of TP-18-C-6 and TP-24-C-8 have been isolated and identified by x-ray diffraction.The complex formation constants, determined by d. c. polarography in methanol/benzene (80:20 v/v), depend not only on the ring size but also on the number and kind of substituents as well as their steric arrangement.The derivatives of 18-C-6 form the most stable complexes with K+, Sr2+, Ba2+, and Pb2+.The derivatives of 24-C-8 prefer K+, Rb+, and Ba2+.