141916-53-2Relevant articles and documents
A general, enantioselective synthesis of 2-substituted thiomorpholines and thiomorpholine 1,1-dioxides
Reed, Carson W.,Lindsley, Craig W.
, (2019/09/10)
In the course of our drug discovery programs, we had need to access chiral, 2-substituted thiomorpholines and their oxidized congeners, thiomorpholine 1,1-dioxides. Here, we disclose a high-yielding, general protocol for the enantioselective synthesis of
A general, enantioselective synthesis of protected morpholines and piperazines
O'Reilly, Matthew C.,Lindsley, Craig W.
, p. 2910 - 2913 (2012/08/14)
A short, high yielding protocol has been developed for the enantioselective and general synthesis of C2-functionalized, benzyl protected morpholines and orthogonally N,N′-protected piperazines from a common intermediate.