1419170-27-6

Basic information

• Product Name: 2-[4-(2-carboxyethyl)-5-{5-[3-(2-carboxyethyl)-5-(2-carboxyphenyl)thiophen-2-yl]thiophen-2-yl}thiophen-2-yl]benzoic acid
• Synonyms: 2-[4-(2-carboxyethyl)-5-{5-[3-(2-carboxyethyl)-5-(2-carboxyphenyl)thiophen-2-yl]thiophen-2-yl}thiophen-2-yl]benzoic acid
• CAS NO: 1419170-27-6
• Molecular Weight: 632.736
• Mol File: 1419170-27-6.mol

Chemical Properties

• CAS DataBase Reference: 2-[4-(2-carboxyethyl)-5-{5-[3-(2-carboxyethyl)-5-(2-carboxyphenyl)thiophen-2-yl]thiophen-2-yl}thiophen-2-yl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(2-carboxyethyl)-5-{5-[3-(2-carboxyethyl)-5-(2-carboxyphenyl)thiophen-2-yl]thiophen-2-yl}thiophen-2-yl]benzoic acid(1419170-27-6)
• EPA Substance Registry System: 2-[4-(2-carboxyethyl)-5-{5-[3-(2-carboxyethyl)-5-(2-carboxyphenyl)thiophen-2-yl]thiophen-2-yl}thiophen-2-yl]benzoic acid(1419170-27-6)

Safety Data

• Hazardous Substances Data: 1419170-27-6(Hazardous Substances Data)

Upstream product

• 1419172-26-1 C₃₆H₃₂O₈S₃ 
• 1419171-80-4 methyl 3-(2-{5-[3-(3-methoxy-3-oxopropyl)thiophen-2-yl]thiophen-2-yl}thiophen-3-yl)propanoate 
• 1195-52-4 trans-3-(3-thienyl)acrylic acid 
• 16378-06-6 3-(3-thienyl)propanoic acid 
• 179932-05-9 3-Thiophen-3-yl-propionic Acid Methyl Ester 
• 1419171-81-5 C₈H₉BrO₂S 
• 1419171-82-6 methyl 3-(5-bromo-2-{5-[5-bromo-3-(3-methoxy-3-oxopropyl)thiophen-2-yl]thiophen-2-yl}thiophen-3-yl)propanoate 

Relevant articles and documents

NOVEL COMPOUNDS AND THEIR USE IN THERAPY

The present invention relates to novel chemical compounds formula (I) (C)n-B-(A)m-B-(C)n (I) wherein m is 0 or 1, and n is independently 0, 1, 2 or 3, A, each B and each C are independently selected from phenylene and five-and six-membered heteroaromatic rings, and for a terminal ring B or C also from bicyclic heteroaromatic fused rings having seven to ten ring members, wherein the bond between at least two of the rings A to C may be replaced by a carbonyl group (-CO-), wherein at least two of the rings A to C are substituted with one or two groups R, and wherein each ring A to C further optionally is substituted with one or two groups R1. The compounds are useful in therapy, especially therapy of a mammal suffering from a disease involving misfolded or aggregated forms of proteins.

NOVEL THIOPHENE COMPOUNDS AND METHOD FOR IN VIVO IMAGING

The present invention relates to novel labelled compounds of formula (I) (C)n-B-(A)m-B-(C)n (I) wherein m is 0 or 1, and n is independently 0, 1, 2 or 3, A, each B and each C are independently selected from phenylene and five- and six-membered heteroaromatic rings, and for a terminal ring B or C also from bicyclic heteroaromatic fused rings having seven to ten ring members, wherein the bond between at least two of the rings A to C may be replaced by a carbonyl group ( -CO- ), wherein at least two of the rings A to C are substituted with one or two groups R, and wherein each ring A to C further optionally is substituted with one or two groups R1, for use in imaging amyloid deposits and aggregated protein in living patients. The invention further relates to imaging methods using labelled or unlabelled compounds of formual I and the use of unlabelled compounds in such methods.