141964-53-6

Basic information

• Product Name: Benzeneacetic acid, a-methyl-, 4-methoxyphenyl ester, (S)-
• CAS NO: 141964-53-6
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol File: 141964-53-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-methyl-, 4-methoxyphenyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-methyl-, 4-methoxyphenyl ester, (S)-(141964-53-6)
• EPA Substance Registry System: Benzeneacetic acid, a-methyl-, 4-methoxyphenyl ester, (S)-(141964-53-6)

Safety Data

• Hazardous Substances Data: 141964-53-6(Hazardous Substances Data)

Upstream product

• 3893-35-4 1-diazo-1-phenyl-2-propanone 
• 150-76-5 4-methoxy-phenol 
• 15231-78-4 2.2-dimethyl-5-phenyl-1,3-dioxane-4,6-dione 
• 24131-01-9 2,2,5-trimethyl-5-phenyl-1,3-dioxane-4,6-dione 
• 36065-28-8 (2S)-1-(4-methoxyphenyl)-2-phenylpropan-1-one 

Relevant articles and documents

Synthesis of Chiral Esters via Asymmetric Wolff Rearrangement Reaction

The first asymmetric Wolff rearrangement reaction that directly converts α-diazoketones into broadly useful chiral α,α-disubstituted carboxylic esters with high enantioselectivities (up to 97.5:2.5 er) is reported. The cascade reaction proceeds through the seamless combination of visible-light-induced formation of the ketene intermediate and asymmetric ketene esterification using a readily available benzotetramisole-type catalyst.

New optical resolution method based on the formation of a solid solution. Optical resolution of racemic 1-(4-methylthiophenyl)-2-phenylpropan-1-one by co-crystallization with (+)-1-(4-methoxyphenyl)-2-phenylpropan-1-one

Crystallization of ketone S-(+)-1 in the presence of a small amount of it sulfur analogue (±)-2 afforded a solid solution containing 8% of S-(+)-2; the latter was isolated in enantiomerically pure form by column chromatography. This simple optical resolut