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Deoxycorticosterone sulfate (DOCS) is a naturally occurring steroid hormone derived from the adrenal cortex, playing a crucial role in the regulation of blood pressure, electrolyte balance, and stress response. It is a sulfated form of deoxycorticosterone, which is a mineralocorticoid hormone. DOCS is involved in the maintenance of sodium and potassium levels in the body, thereby influencing fluid balance and blood volume. Additionally, it has been implicated in the pathophysiology of certain conditions, such as congenital adrenal hyperplasia and Cushing's syndrome. The measurement of DOCS in blood samples can be a valuable diagnostic tool for assessing adrenal function and diagnosing related disorders.

1420-82-2

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1420-82-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1420-82-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,2 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1420-82:
(6*1)+(5*4)+(4*2)+(3*0)+(2*8)+(1*2)=52
52 % 10 = 2
So 1420-82-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H30O6S/c1-20-9-7-14(22)11-13(20)3-4-15-16-5-6-18(19(23)12-27-28(24,25)26)21(16,2)10-8-17(15)20/h11,15-18H,3-10,12H2,1-2H3,(H,24,25,26)/t15-,16-,17-,18+,20-,21-/m0/s1

1420-82-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Desoxycorticosteronsulfat

1.2 Other means of identification

Product number -
Other names Sulfuric acid mono-[2-((10R,13S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1420-82-2 SDS

1420-82-2Upstream product

1420-82-2Downstream Products

1420-82-2Related news

Origin of deoxycorticosterone sulfate (cas 1420-82-2) (DOC-SO4) in plasma of pregnant women: Pregnenolone-3,21-disulfate is a placental precursor of DOC-SO409/30/2019

The plasma levels of deoxycorticosterone sulfate (DOC-SO4) in near-term pregnant women are ∼100 times those in plasma of men or non-pregnant women. Yet, neither the tissue site of synthesis nor the precursor of DOC-SO4 that enters maternal plasma is known. Several potential sources have been ex...detailed

Origin of deoxycorticosterone and deoxycorticosterone sulfate (cas 1420-82-2) in human pregnancy: Absence of steroid 21-sulfatase activity in sulfatase-deficient placenta09/29/2019

The activity of steroid 21-sulfatase, the enzyme that catalyzes the hydrolysis of deoxycorticosterone sulfate (DOC-SO4) is demonstrable in human placenta. Thus, it is possible that this placental enzyme, by way of the hydrolysis of either DOC-SO4 or 21-hydroxypregnenolone mono- or di-sulfate of ...detailed

Metabolic clearance rate of plasma deoxycorticosterone sulfate (cas 1420-82-2) in men and women09/27/2019

In the present investigation, we determined the metabolic clearance rate of plasma deoxycorticosterone sulfate in adult men and nonpregnant women and in one woman pregnant at 42 weeks gestation with an anencephalic fetus. The values obtained varied from 618 to 1070 l/24 h. The metabolic clearanc...detailed

Umbilical cord plasma concentrations of deoxycorticosterone sulfate (cas 1420-82-2) in anencephalic fetuses☆09/25/2019

In the present investigation, we determined the levels of deoxycorticosterone sulfate in mixed umbilical cord plasma of anencephalic abortuses and newborn infants. The anencephalic fetus is an interesting model with respect to the production of deoxycorticosterone and deoxycorticosterone sulfate...detailed

A radioimmunoassay for deoxycorticosterone sulfate (cas 1420-82-2) without hydrolysis09/24/2019

The hapten of deoxycorticosterone sulfate was synthesized and linked to the carrier protein through the C-4 position on the steroid nucleus. The antisera raised against this antigen in guinea pigs exhibited high affinity (Ka=1.86 × 109 M−1) and excellent specificity for deoxycorticosterone sulf...detailed

1420-82-2Relevant academic research and scientific papers

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