142004-02-2

Upstream product

• 142004-01-1 1-nitro-2,3,4,5-tetramethoxybenzene 
• 142004-00-0 2-hydroxy-1-nitro-3,4,5-trimethoxybenzene 
• 52978-83-3 2,3,4-trimethoxy-6-nitrobenzaldehyde 

Downstream Products

• 1137557-65-3 3-oxo-N-(2,3,4,5-tetramethoxyphenyl)butanamide 

Relevant academic research and scientific papers

Multisubstituted 1-hydroxy-9-acridones with anticancer activity

The present invention provides a compound having the structure: STR1 The present invention also provides a method for synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method. The present invention further provides a pharmaceutical composition comprising the above compounds. Lastly, the present invention provides a method of inhibiting growth of tumor cells.

Synthesis of the acridone alkaloids glyfoline and congeners. Structure- activity relationship studies of cytotoxic acridones

Glyfoline (4, 1,6-dihydroxy-10-methyl-2,3,4,5-tetramethoxyacridin-9-one) and its congeners were synthesized for evaluation of their cytotoxicity. A detailed structure-activity relationships (SAR) of these acridone derivatives were also studied. To study t