142033-80-5

Upstream product

• 25152-96-9 N⁶-benzoyl-3'-(methoxyacetyl)-2'-deoxyadenosine 
• 84416-85-3 [5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite 

Downstream Products

• 141928-26-9 5'-O-(N⁶-benzoyl-3'-O-(diisopropylaminomethoxyphosphino)-2'-deoxyadenosyl) 3'-O-<5'-O-(dimethoxytrityl)thymidine> O-methyl phosphorothioate 
• 141955-64-8 5'-O-(N⁶-benzoyl-2'-deoxyadenosyl) 3'-O-<5'-O-(dimethoxytrityl)thymidine> O-methyl phosphorothioate 
• 130767-64-5 Thiophosphoric acid O-[(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester O'-[(2R,3S,5R)-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester 

Relevant academic research and scientific papers

Site-specific labeling of DNA sequences containing phosphorothioate diesters

A phosphorothioate diester can be incorporated site-specifically into DNA sequences to provide a nucleophilic site that is amenable to alkylation by labels containing haloacetamide, aziridine sulfonamide, or γ-bromo-α,β-unsaturated carbonyl functionalitie