Site-specific labeling of DNA sequences containing phosphorothioate diesters

DOI: 10.1021/ja00040a004

Source and publish data:

Journal of the American Chemical Society p. 5509 - 5517 (1992)

Update date:2022-09-26

Topics:

Authors:

Fidanza, Jacqueline A.

Ozaki, Hiroaki

McLaughlin, Larry W.

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Article abstract of DOI:10.1021/ja00040a004

A phosphorothioate diester can be incorporated site-specifically into DNA sequences to provide a nucleophilic site that is amenable to alkylation by labels containing haloacetamide, aziridine sulfonamide, or γ-bromo-α,β-unsaturated carbonyl functionalitie

Full text of DOI:10.1021/ja00040a004

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