14204-97-8 Usage
Uses
Used in Organic Synthesis:
5-Nitro-6-methylaminoquinoline is used as a synthetic building block for the development of complex organic molecules. Its unique chemical structure, featuring a nitro group and a methylamino group attached to a quinoline core, allows it to participate in a range of chemical reactions, facilitating the synthesis of diverse organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Nitro-6-methylaminoquinoline is utilized as an intermediate in the synthesis of various pharmaceutical compounds. Its ability to form a variety of chemical bonds and its compatibility with different reaction conditions make it a versatile component in the development of new drugs and therapeutic agents.
Used in Chemical Research:
5-Nitro-6-methylaminoquinoline also finds application in chemical research, where it is employed as a model compound to study various reaction mechanisms and to understand the behavior of similar molecules under different conditions. This helps researchers to develop a deeper understanding of the underlying chemistry and to design more efficient synthetic routes for the production of target molecules.
Used in Dye and Pigment Industry:
The dark yellow crystalline nature of 5-Nitro-6-methylaminoquinoline makes it a potential candidate for use in the dye and pigment industry. Its color properties can be exploited to create new dyes and pigments for various applications, such as in the textile, plastics, and printing industries.
Used in Material Science:
In the field of material science, 5-Nitro-6-methylaminoquinoline can be used to develop novel materials with specific properties. Its unique chemical structure and reactivity can be leveraged to create materials with tailored characteristics, such as improved conductivity, enhanced stability, or specific optical properties, for use in various technological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 14204-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,0 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14204-97:
(7*1)+(6*4)+(5*2)+(4*0)+(3*4)+(2*9)+(1*7)=78
78 % 10 = 8
So 14204-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H9N3O2/c1-11-9-5-4-8-7(3-2-6-12-8)10(9)13(14)15/h2-6,11H,1H3
14204-97-8Relevant academic research and scientific papers
HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF
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Page/Page column 42-43, (2012/07/27)
Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.
Synthetic Routes to the Carcinogen IQ and Related 3H-Imidazoquinolines
Ronne, Erik,Grivas, Spiros,Olsson, Kjell
, p. 823 - 830 (2007/10/02)
2-Amino-3-methyl-3H-imidazoquinoline (IQ, 1a) and four new IQ homologues, viz. its 7-methyl, 8-methyl, 9-methyl and 7,9-dimethyl derivatives 1c-1f, have been conveniently synthesized from the appropriate 6-methoxyquinolines 3 rather than from the p
Oxidative Methylamination of Nitroquinolines
Wozniak, Marian,Grzegozek, Maria
, p. 823 - 830 (2007/10/02)
3-, 5-, 6-, 7- and 8-nitroquinoline as well as 5,7- and 6,8-dinitroquinoline are methylaminated with a liquid methylamine solution of potassium permanganate (LMA/PP) to the corresponding mono- and bis(methylamino)-substituted compounds. 2-Nitroquinoline is aminated with LMA/PP to 2-(methylamino)quinoline.The intermediate methylamino ?-adducts of 3-nitro- and 5,7- and 6,8-dinitroquinoline are detected by 1H-NMR spectroscopy.Quantum chemical calculations for the mononitroquinolines suggest that the experimentally observed regioselectivity of the methylamination is controlled by an interaction of frontal molecular orbitals (FMO) of the reagents. Key Words: Methylaminations / ?-Adducts, methylamino / Calculations, FMO / Quinolines / Aminations
BIOLOGICAL FORMATION AND CHEMICAL SYNTHESIS OF 2-AMINO-3,6-DIHYDRO-3-METHYL-7H-IMIDAZOLOQUINOLIN-7-ONE, THE MAJOR METABOLITE OF THE DIETARY CARCINOGEN 2-AMINO-3-METHYL-3H-IMIDAZOLOQUINOLINE (IQ) BY NORMAL INTESTINAL BACTERIA
Bashir, Mohammad,Kingston, David G. I.,Carman, Robert J.,Tassell, Roger L. van,Wilkins, Tracy D.
, p. 2877 - 2886 (2007/10/02)
2-Amino-3,6-dihydro-3-methyl-7H-imidazoloquinolin-7-one (2) has been synthesized from 6-bromo-5-nitroquinoline in seven steps.Biological formation of 2 from IQ (1) involves the addition of water from the medium, followed by oxidation.
