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1420478-87-0

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1420478-87-0 Usage

Description

(S)-benzyl 2-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is a complex organic chemical compound characterized by the presence of a benzyl group, a pyrrolidine-1-carboxylate moiety, and a 1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl group. (S)-benzyl 2-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is distinguished by its stereochemistry, with the (S)-configuration indicating a specific spatial arrangement of its atoms. Its structural features suggest potential roles in medicinal chemistry, where it could serve as a precursor or a scaffold for the synthesis of pharmaceuticals or as a probe in biological research.

Uses

Used in Medicinal Chemistry:
(S)-benzyl 2-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is used as a building block for the development of new pharmaceuticals due to its unique structural elements that may facilitate novel interactions with biological targets.
Used in Research and Development:
In the pharmaceutical industry, (S)-benzyl 2-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is used as a research tool for studying biological systems, potentially aiding in the discovery of new mechanisms of action or the identification of new drug targets.
Used in Drug Design and Synthesis:
(S)-benzyl 2-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is utilized in the design and synthesis of drugs, where its specific chemical properties may contribute to the creation of molecules with desired therapeutic effects and improved pharmacokinetic profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 1420478-87-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,0,4,7 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1420478-87:
(9*1)+(8*4)+(7*2)+(6*0)+(5*4)+(4*7)+(3*8)+(2*8)+(1*7)=150
150 % 10 = 0
So 1420478-87-0 is a valid CAS Registry Number.

1420478-87-0Relevant articles and documents

Method for preparing Acalabrutinib, in particular to method for preparing Acalabrutinib

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, (2020/07/24)

The invention relates to the field of chemical synthesis, in particular to a chemical synthesis method for preparing Acalabrutinib. The synthesis method of the compound 3 is optimized, wherein the cyano compound 2 is reduced to obtain the compound 3 by adopting a method of generating borane in situ under the conditions of indium trichloride and sodium borohydride. The method is simple and convenient to operate, a special reaction container and hydrogen are not needed for reduction, a high-risk material catalyst nickel is prevented from being adopted, and large-scale production is facilitated.In the preparation of the compound 15, water is used as a solvent, equivalent hydrogen peroxide is added to react the compound 13 with the compound 14 to prepare the compound 15, so that the method iseconomic and environment-friendly, the post-treatment is simple and convenient, and the reaction liquid is directly subjected to centrifugal operation; in addition, the yield is high and can reach 90% or above; and the compound 15 is high in purity and does not need to be further purified, so that the technology can satisfy the requirements of industrial production.

PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-A]-PYRAZIN-1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE

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, (2020/03/23)

The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.

IMIDAZOPYRAZINE INHIBITORS OF INTERLEUKIN-2-INDUCIBLE T-CELL KINASE

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, (2020/01/08)

In some embodiments, the invention relates to an interleukin-2- inducible T-cell kinase (ITK) inhibitor of formula (I) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in the trea

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