867165-55-7

Basic information

• Product Name: 2-((3-chloropyrazin-2-yl)Methyl)isoindoline-1,3-dione
• Synonyms: 2-((3-chloropyrazin-2-yl)Methyl)isoindoline-1,3-dione
• CAS NO: 867165-55-7
• Molecular Formula: C13H8ClN3O2
• Molecular Weight: 273.67452
• EINECS: -0
• Mol File: 867165-55-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-((3-chloropyrazin-2-yl)Methyl)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((3-chloropyrazin-2-yl)Methyl)isoindoline-1,3-dione(867165-55-7)
• EPA Substance Registry System: 2-((3-chloropyrazin-2-yl)Methyl)isoindoline-1,3-dione(867165-55-7)

Safety Data

• Hazardous Substances Data: 867165-55-7(Hazardous Substances Data)

Usage

Structure

Isoindoline-1,3-dione derivative with a 3-chloropyrazine moiety

Usage

Medicinal chemistry and drug discovery, potential drug candidate for the treatment of various diseases

Application

Research and development as a building block for the synthesis of novel chemical entities with potential biological activity

Significance

Unique structure and potential pharmacological properties, interesting target for further investigation and development in the pharmaceutical industry.

Upstream product

• 1074-82-4 potassium phtalimide 
• 45660-95-5 2-chloro-3-(chloromethyl)pyrazine 
• 14508-49-7 2-chloropyrazin 
• 19194-55-9 O-ethyl S-phthalimidomethyl dithiocarbonate 
• 95-58-9 2-chloro-3-methylpyrazine 
• 1289386-07-7 2-(3-chloropyrazinyl)methyl bromide 
• 136918-14-4 phthalimide 
• 89283-32-9 (3-chloropyrazin-2-yl)methanol 

Downstream Products

• 1320266-92-9 8-chloro-1-iodo-3-isopropylimidazo[1,5-a]pyrazine 
• 1320266-94-1 1-iodo-3-isopropylimidazo[1,5-a]pyrazin-8-amine 
• 1320266-96-3 C₁₀H₁₄ClN₃O 
• 1320266-90-7 8-chloro-3-isopropylimidazo[1,5-a]pyrazine 
• 1418307-17-1 benzyl (S)-2-(((3-chloropyrazin-2-yl)methyl)carbamoyl)pyrrolidine-1-carboxylate 
• 1418307-18-2 (S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid benzyl ester 
• 1420478-87-0 benzyl (2S)-2-(1-bromo-8-chloro-imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate 
• 1420478-88-1 benzyl (2S)-2-(8-amino-1-bromo-imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate 
• 1419221-77-4 benzyl (3R)-3-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate 
• 1419221-78-5 benzyl (3R)-3-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate 
• 1419221-79-6 benzyl (3R)-3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate 
• 1419221-80-9 benzyl (R)-3-(8-amino-1-bromoimidazo[1,5-a]-pyrazin-3-yl)piperidine-1-carboxylate 
• 1418307-23-9 benzyl (2S)-2-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate 
• 1419221-81-0 benzyl (3R)-3-(8-amino-1-(4-[(pyridin-2-yl)carbamoyl]phenyl)imidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate 

Relevant articles and documents

Xanthate-mediated intermolecular alkylation of pyrazines

An expedient approach for the intermolecular C-H functionalization of pyrazines and other heteroarenes by the radical chemistry of xanthates is reported. Incorporation of a multitude of functional alkyl groups onto these heteroarenes proceeds in good yiel

Compound used as Bruton tyrosine kinase inhibitor, and preparation method and application of compound

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Process to prepare substituted imidazopyrazine compounds

A method of preparing wherein, X=Cl, Br, I, comprises the step of treating with N-chloro-, N-bromo-, or N-iodosuccinimide in a compatible solvent such as dimethylformamide (DMF) at 0-60° C. followed by halogenation.