14208-07-2

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 13 carbon (C) atoms, 22 hydrogen (H) atoms, and 2 nitrogen (N) atoms.

Explanation

Dihydropyridines are a class of chemical compounds that have a six-membered ring with two nitrogen atoms and two double bonds, with two additional hydrogen atoms. 1-[3-(piperidin-1-yl)propyl]-1,2-dihydropyridine belongs to this class.

Explanation

Calcium channel blockers are a type of medication that inhibit the movement of calcium ions into cells, particularly smooth muscle and cardiac muscle cells. 1-[3-(piperidin-1-yl)propyl]-1,2-dihydropyridine is a part of this group of compounds.

Explanation

The compound primarily works by affecting the influx of calcium ions into smooth muscle cells and cardiac muscle cells, which leads to vasodilation and decreased cardiac contractility.

Explanation

The compound contains a piperidine group, which is a heterocyclic amine consisting of a six-membered ring with one nitrogen atom. This group can have various pharmacological effects.

Explanation

The specific properties and potential uses of 1-[3-(piperidin-1-yl)propyl]-1,2-dihydropyridine would need to be further investigated through research and testing to determine its effectiveness and safety.

Explanation

The exact pharmacological effects of 1-[3-(piperidin-1-yl)propyl]-1,2-dihydropyridine are not known and would require further research to understand its potential therapeutic applications.

Explanation

Further research and testing are necessary to explore the compound's properties, potential uses, and any possible side effects or risks associated with its use.

Chemical Class

Dihydropyridine derivative

Functionality

Calcium channel blocker

Mechanism of Action

Affecting calcium ion influx

Structural Feature

Piperidine group

Potential Uses

Further investigation required

Pharmacological Effects

Unknown at this stage

Research Status

Investigation and testing needed

Upstream product

• 110-86-1 pyridine 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 10035-10-6 hydrogen bromide 
• 18820-82-1 Pyridine hydrobromide 

Relevant academic research and scientific papers

A study about excellent xanthine oxidase inhibitory effects of new pyridine salts

A series of pyridine salts were synthesized containing vitamin B3 (niacin), isonicotinonitrile, and non-substituted pyridine fragment from reactions of 1,3-dibromopropane, 1,4-dibromobutane, and 4,4′-bis(chloromethyl)-1,1′-biphenyl reactants with pyridine

Construction and isomeric transformation of polyoxometalates directed by 1,ω-bis(pyridinium)alkane templates

Ten novel inorganic-organic hybrid polyoxometalates, namely, [1,3-bis(pyridinium) propane]2[α-Mo8O26] (1), [1,4-bis(pyridinium)butane]2[1D-Mo8O26] (2), [1,5-bis(pyridinium)pentane]2[-Mo8O26] (3), [1,6-bis(pyridinium)hexane]2[1D-Mo8O26] (4), [1,7-bis(pyridinium)heptane]2[β-Mo8O 26] (5), [1,8-bis(pyridinium)octane]2[-Mo 8O26] (6), [1,9-bis(pyridinium)nonane] 2[(α + β)-Mo8O26] (7), [1,10-bis(pyridinium)decane]2[β-Mo8O26] (8), [1,11-bis(pyridinium)undecane]2[β-Mo8O 26] (9), [1,12-bis(pyridinium)dodecane]2[γ-Mo 8O26] (10), (Scheme 1) were synthesized by cation templated self-assembly with octamolybdate anions under hydrothermal reaction conditions. Crystal data analysis revealed that these compounds were all composed of discrete organic cations and polyacid anions [Mo8O 26]4- interacting by electrostatic and hydrogen bond interactions. Interestingly in these compounds the anion fraction could take on α-, β-, -, γ-[Mo8O26]4- 0D isomers or rare 1D- polymeric frameworks with a simple length modification of the alkane components. Moreover, these polyacid compounds had definite catalytic activities on the oxidation reaction of acetaldehyde to acetic acid and the relationship of structure/catalytic activities were initially demonstrated.

Synthesis and properties of new (μ-oxo)bis[trichloroferrate(III)] dianion salts incorporated with dicationic moiety

New (μ-oxo)bis[trichloroferrate(III)] dianions-based ionic compounds that contain various counterdications were synthesized and characterized with regards to their crystal structures, thermal properties, and magnetic susceptibility. These salts are soluble in polar solvents such as methanol and water. The melting point of these compounds is affected by the dication following the order of triphenylphosphinium > pyridinium > imidazolium dications, and symmetrical dicationic salts > unsymmetrical ones. In these compounds, the trichloroferrate dianion exists in either a linear or a bent form, which is affected by the dications. Interestingly, the dicationic diferrate compounds show magnetic coupling constants fairly smaller than those reported in literature for diferrate salts in which monocations are the counterion. Furthermore, unlike the diferrate salts associated with separate monocations, the linear diferrate dicationic compounds show magnetic coupling constant lower than that of bent diferrate dicationic salts.

The Thermal and Photochemical Behavior of the Cyclomers Derived from 1,1'-(1,3-Propanediyl)bis(pyridinyl) Diradicals

Reduction of 1,1'-(1,3-propanediyl)bis(pyridinium) dibromide (5a) with sodium amalgam afforded the meso- and dl-cyclomers formed by intramolecular cyclization of the diradical (2a).The meso-cyclomer (6a) was thermally converted into the dl-cyclomer (7a), while retroversion of 7a into 6a was achieved photochemically.Reduction of the 4,4'-dimethyl (5b) and 4,4'-di-t-butyl (5c) derivatives of 5a similarly afforded the corresponding meso-(6b and 6c) and dl-(7b and 7c) cyclomers, which can be interconverted to each other.Using NMR spectroscopy to follow the reaction theenergies for thermal conversion of meso- to dl-cyclomers were found to be 58.6, 74.5, and 84.5 kJ mol-1 for 6a, 6b, 6c, respectively.Photodissociation of the cyclomers at -196 deg C gave the diradicals (2a-2c), which showed characteristic triplet ESR spectra.The ESR spectra for both 2a and 2b indicated that there were two conformation, each with different zero-field splitting parameters, in 2-methyltetrahydrofuran glass.In contrast, the ESR spectrum of 2c indicated that it has only one conformation.The 4,4'-bis(methoxycarbonyl) derivative (2d) of 2a also forms cyclomers which, upon photolysis, regenerate the diradical.It was concluded that 1,1'-(1,3-propanediyl)bis(pyridinyl) diradicals are substantially in thermal equilibrium with the cyclomers.

Halobismuthates with bis(pyridinium)alkane cations: Correlations in crystal structures and optical properties

A series of four chloro- and bromobismuthates with bis(pyridinium)alkane cations (Py(CH2)nPy)2+(Cn) and (4-PyH)(CH2)n(4-PyH)2+(H2Cn) were synthesized and characterized. Analysis of their crystal structures, as well as previously reported data, results in establishment of correlations between the type of halobismuthate anion and the nature of cation. Luminescent properties of obtained compounds are reported and discussed.

Bromoantimonates with bis(pyridinium)-type dications obtained via oxidation by dibromine: Diverse structural types and features of interactions pattern

Bromoantimonate(III) species, which can be generated in solution by reaction of Sb2O3 and HBr, can be oxidized by Br2 into mixed-valence complexes or bromoantimonates(V). The outcome of these reactions governs by the nature of cation which salt is used for isolation of solid complexes. Using bromides of three 1,n-bis(pyridinium)alkane cations (PyCn, where X = 2, 3 and 4), we isolated three complexes: (PyC2){[SbBr6](Br3)} (1), (PyC3)2[Sb2Br9][SbBr6] (2) and (PyC4){[SbBr6](Br3)} (3), respectively. Their structures were determined by X-ray diffractometry. For 1 and 3, the energies of non-covalent interactions between tribromide units and [SbBr6]? were estimated using DFT calculations.

Mono- and Binuclear Chloride and Bromide Complexes of Bi(III) with Double-Charged Cations Based on Pyridine: Syntheses and Crystal Structures

Abstract: The reactions of solutions obtained by the reactions of Bi2O3 with 2 M HCl and HBr with the salts containing bis(pyridyl)alkane cations afford mono- and binuclear halide complexes (Py-(CH2)3-Py)3[Bi2Br9]2 (I), (H3O)(Py-(CH2)4-Py)[BiCl6] ? 3H2O (II), and (H2Bpp)2[Bi2Br10] ? 2H2O (Bpp is 1,3-bis(4-pyridyl)propane) (III). The structures of the synthesized compounds are determined by X-ray diffraction analysis (СIF files CCDC no. 1583338–1583340, respectively).

CRYSTAL STRUCTURES OF POLYBROMIDE SALTS OF BIS(PYRIDYL)ALKANE DICATIONS

Abstract: Reactions of solutions of 1,1′-(alkane-1,х-diyl)-bis(pyridinium) dibromides ((PyCx)Br2) with 1M Br2 in HBr result in the formation of tribromides (PyCx)(Br3)2 (x?=?3 (1), 4 (2), 5 (3)) and pentabromide (PyC6)(Br5)2 (4). Their structures are investigated by X-ray crystallography. The structure of 4 contains noncovalent Br?Br interactions linking Br5- anions into two-dimensional supramolecular associates.

Double three bromo 1,3-di-pyridine salt-based propane and its preparation method, method of use, recovery method and application

The invention discloses a double tribromo 1,3-bipyridine onium salt dimethylmethane, and a preparation method, an application method, a recovery method and application thereof. The preparation method comprises the following steps: dissolving 1,3-bipyridine onium salt dimethylmethane by using water, and then adding potassium bromide; adding potassium peroxymonosulfate sulfate compound brine solution to prepare a clear solution after dissolving potassium bromide, and then stirring and reacting at -10 to 0 DEG C until solid is separated out; separating out solid, so as to obtain the double tribromo 1,3-bipyridine onium salt dimethylmethane. The product can be used for preparing isothiocyanate, aromatic thiourea or acetanilide. The preparation method disclosed by the invention is mild in condition, and simple to operate the reaction process, and raw materials are easily available. The double tribromo 1,3-bipyridine onium salt dimethylmethane not only can be used as a brominating reagent, but also can be used as organic synthesis intermediates, meanwhile, the reaction efficiency is improved, and the double tribromo 1,3-bipyridine onium salt dimethylmethane is convenient to recover and can be recycled.

Synthesis and properties of new tetrachlorocobaltate (II) and tetrachloromanganate (II) anion salts with dicationic counterions

New tetrachlorocobaltate (II) and tetrachloromanganate (II) ionic compounds containing various counterdications were synthesized and characterized. These salts are soluble in polar solvents such as methanol and water. Physical properties such as thermal stability, melting point, and magnetic susceptibility of these salts depend on the cation or anion structure. The thermal stability of the phosphinium or imidazolium based salts is higher than that of the pyridinium or triethylaminonium analogues. The melting point of these compounds is following the order of triphenylphosphinium > pyridinium > imidazolium dications, and symmetrical dicationic salts > unsymmetrical ones. The magnetic susceptibility (χMT values) of tetrachloromanganate (II) anions-based salts is higher than that of tetrachlorocobaltate (II) anions-based salts. These dicationic salts exhibit weak antiferromagnetic interactions and have higher magnetic susceptibility than that of the previously reported tetrachloromanganate (II) and tetrachlorocobaltate(II) salts with monocationic counterion.