18820-82-1

Basic information

• Product Name: Pyridine hydrobromide
• Synonyms: Pyrridinbromohydrate;Pyridine·hydrogen bromide;Einecs 242-600-7;Pyridine, hydrobromide (1:1);Pyridine hydrobromide,Pyridinium bromide;PHBR;PYRIDINIUM BROMIDE;PYRIDINE HYDROBROMIDE
• CAS NO: 18820-82-1
• Molecular Formula: Br*C₅H₆N
• Molecular Weight: 160.01
• EINECS: 242-600-7
• Product Categories: Pyridinium Compounds;Naphthyridine,Quinoline;OLED materials,pharm chemical,electronic;Pyridine
• Mol File: 18820-82-1.mol

Chemical Properties

• Melting Point: 200 °C (dec.)(lit.)
• Boiling Point: 115.3 °C at 760 mmHg
• Flash Point: 20 °C
• Appearance: Colorless liquid
• Density: 0.956 g/cm³
• Vapor Pressure: 22.8mmHg at 25°C
• Storage Temp.: Store under Nitrogen
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• BRN: 3615336
• CAS DataBase Reference: Pyridine hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine hydrobromide(18820-82-1)
• EPA Substance Registry System: Pyridine hydrobromide(18820-82-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3-10
• TSCA: Yes
• Hazardous Substances Data: 18820-82-1(Hazardous Substances Data)

Usage

Uses

1. Research Chemical:
Pyridine hydrobromide is used as a research chemical for conducting scientific investigations and experiments in the field of chemistry.
2. Chemical Synthesis Studies:
In the chemical synthesis industry, pyridine hydrobromide is used as a reagent for various chemical reactions, particularly in the synthesis of new compounds.
3. Brominations of Ketones:
Pyridine hydrobromide is particularly useful for brominations of ketones on a micro or semimicro scale, making it a valuable tool in the synthesis of organic compounds.
4. Pharmaceutical Industry:
Pyridine hydrobromide may also be used in the pharmaceutical industry for the development and synthesis of new drugs, given its versatility as a reagent in chemical reactions.

InChI:InChI=1/C5H5N.BrH/c1-2-4-6-5-3-1;/h1-5H;1H

Upstream product

• 110-86-1 pyridine 
• 79-27-6 1,1,2,2-tetrabromoethane 
• 14208-08-3 1,1'-(butane-1,4-diyl)bis-pyridine (double di(bromide)) 
• 53394-57-3 1,5-bis(pyridinium)-pentane dibromide 
• 2675-31-2 benzophenone-(4-nitro-phenylhydrazone) 
• 574-61-8 benzophenone N-phenylhydrazone 
• 40594-87-4 N-benzhydrylidene-N'-(4-chlorophenyl)-hydrazine 
• 106046-95-1 N-benzhydrylidene-N'-(4-bromophenyl)-hydrazine 
• 40594-88-5 N-(4-methylphenyl) benzophenone hydrazone 

Downstream Products

• 6318-99-6 1-(2-hydroxy-2-phenylethyl)pyridinium bromide 
• 1191-24-8 (S)-(+)-2-bromooctane 
• 4167-75-3 2-isobutylphenol 
• 4167-74-2 4-isobutylphenol 
• 626-55-1 3-Bromopyridine 
• 625-92-3 3,5-dibromopyridine 
• 39416-48-3 pyridinium hydrobromide perbromide 
• 5834-42-4 3-(4-methoxyphenyl)-2-phenyl-1H-indole 
• 61799-01-7 N-(3,4-dihydroxyphenyl)pyridinium bromide 
• 76494-25-2 N-(2,5-dihydroxyphenyl)pyridinium bromide 
• 109-65-9 1-bromo-butane 
• 7789-60-8 phosphorus tribromide 
• 507-19-7 t-butyl bromide 
• 78-77-3 Isobutyl bromide 

Relevant articles and documents

Pyridinium halides and their mixtures as inhibitors of steel corrosion in sulfuric acid solutions

Mixtures of 1-acylmethylpyridinium halides with equimolar amounts of pyridinium halides were prepared by the Ortoleva-King reaction. The inhibiting effect of various pyridinium halides and their mixtures on corrosion of steel in sulfuric acid solutions was studied.

Synthesis method for pyridine bromate

The invention provides a synthesis method for pyridine bromate. The synthesis method comprises the following steps: (1) adding hydrobromic acid with a concentration of 48 wt% into a reaction kettle, inserting a liquid outlet of a dropwise adding pipe below the liquid level of the hydrobromic acid, dropwise adding pyridine into the hydrobromic acid through the dropwise adding pipe for a reaction, keeping a temperature to be less than or equal to 55 DEG C in the process of the reaction, and adjusting a pH value to 1.5-2.5 after the reaction is finished to obtain a feed liquid; (2) heating and evaporating the feed liquid obtained in the step (1) at a temperature of 60-70 DEG C under a vacuum condition of -0.0095 to -0.085 MPa, feeding the feed liquid to a crystallizing tank after crystals appear, conducting cooling and crystallizing, and then performing centrifuging to obtain solid precipitates and mother liquor; and (3) washing the solid precipitate with pure water or methanol, conducting drying to obtain pyridine bromate, adding activated carbon into the mother liquor for decoloration, and returning the mother liquor for indiscriminate application. The method is convenient for industrial large-scale synthesis, high in quality yield and high in purity.

The effect of organic cations on the electronic, optical and luminescence properties of 1D piperidinium, pyridinium, and 3-hydroxypyridinium lead trihalides

We present a structural and optoelectronic study of 1D piperidinium, pyridinium, and 3-hydroxypyridinium lead trihalides. In contrast to the piperidinium and pyridinium species whose single inorganic chains [PbX31-]n are separated by organic cations, the 3-hydroxypyridinium compound is characterized by double inorganic chains. According to DFT the valence and conduction bands of the piperidinium lead trihalides are composed of occupied p-orbitals of the halogen anions and unoccupied p-orbitals of the Pb2+ cations. In contrast, the pyridinium species feature low-lying cationic energy levels formed from the cation's π?-orbitals. Thus, electronic transitions between the cationic energy levels and valence bands require less energy than valence to conduction band transitions in the case of piperidinium lead trihalides. The presence of an OH group in the pyridinium ring leads to a bathochromic shift of the cationic energy levels resulting in a decreased energy of transitions from the cationic energy levels to the valence band. Electronic transitions predicted by DFT are observable in experimental optical absorption and luminescence spectra. This study paves the way for creation of 1D perovskite-like structures with desired optoelectronic properties.

Protic onium salts-catalyzed synthesis of 5-aryl-2-oxazolidinones from aziridines and CO2 under mild conditions

Protic onium salts, e.g. pyridium iodide, proved to be highly efficient and recyclable catalysts for the selective synthesis of 5-aryl-2-oxazolidinones under a CO2 atmosphere at room temperature, presumably due to aziridine activation assisted by hydrogen bonding on the basis of 1H NMR and in situ FT IR under CO2 pressure study.

Kinetics and mechanism of oxidation of some α-amino acids by pyridinium hydrobromide perbromide

Oxidation of nine α-amino acids by pyridinium hydrobromide perbromide (PHPB) in aqueous acetic acid leads to the formation of the corresponding aldehydes.The reaction is first order with respect to PHPB.Michaelis-Menten type kinetics are observed with respect to some of the amino acids while other amino acids exhibit a second order dependence.The oxidation of perdeuterioglycine showed the absence of a kinetic isotope effect.The effect of solvent composition indicates that the reaction rate increases with an increase in the polarity of the medium.Addition of pyridinium hydrobromide and bromide ion have no effect on the rate of oxidation.The reaction is susceptible to both polar and steric effects of the substituents.It failed to induce polymerization of acrylonitrile.Suitable mechanisms have been proposed.

Kinetics and Mechanism of Oxidation of Aliphatic Aldehydes by Pyridinium Hydrobromide Perbromide

Oxidation of six aliphatic aldehydes by pyridinium hydrobromide perbromide (PHPB) in aqueous acetic acid leads to the formation of the corresponding carboxylic acids.The reaction is first order with respect to PHPB.Michaelis-Menten type kinetics were observed with respect to the aldehyde.The formation constants for the aldehyde-PHPB complexes and the rate of their decomposition, at different temperatures, were evaluated.The oxidation of MeCDO exhibited a substantial kinetic isotope effect.The effect of solvent composition indicated that the transition state is morepolar than the reactants.The role of aldehyde in the oxidation process is discussed.A mechanism involving transfer of a hydride ion from the aldehyde hydrate to the oxidant is proposed.

Gold(I) Complexes derived from Secondary Phosphines: , (-), , and (+). Crystal structure of

The interaction of secondary phosphines with a variety of gold(I) compounds has been studied.In the presence of bases or polar solvents, polymeric gold(I) phosphides are formed.When these are obtained in the absence of additional ligands they are soluble, presumably with ring structures.More usually, insoluble forms are found, presumably with chain structures.The probable formation of these materials from complexes of the type is discussed, and the isolation of the latter complexes (X=Cl or Br, R=Ph or p-tolyl) and of the novel monomeric phosphido-bridged anion (-) is described.In non-polar solvents a series of secondary phosphine complexes is formed, (+) (n=2-4), but that with n=3 appears to be unstable to disproportionation.The compounds are characterised by (31)P n.m.r. and (197)Au Moessbauer spectroscopy, and X-ray crystallography in the case of .

Investigation of Cationic Hydrogen-bonded Systems by Fast Atom Bombardment Mass Spectrometry

Fast atom bombardment mass spectrometry (FABMS) has been used to investigate the hydrogen-bonding of pyridinium and trialkylammonium ions with a range of electron donors.We have studied the effects of matrix liquid, concentration, nature of the anion, and strength of the hydrogen-bond on the observed intensity of the complex peak.The results may be easily rationalized in hydrogen-bonding terms and are in excellent agreement with those of more "conventional" techiques such as i.r. spectroscopy.

EFFICIENT SYNTHESIS OF ARYLAZO-METHOXY-DIPHENYLMETHANES

Benzophenone arylhydrazones 1 react with bromine and pyridine to give 1-(arylazo-diphenylmethyl)-pyridinium bromides 2 along with pyridine hydrobromide; these salt mixtures upon treatment with methanol yield arylazo-methoxy-diphenylmethanes 3.