142087-76-1

Upstream product

• 67-56-1 methanol 
• 538311-43-2 mesityl(α-methylbenzylamino)phenylphosphine 
• 1579997-30-0 C₃₄H₃₁O₃P 
• 124-41-4 sodium methylate 
• 1579997-16-2 C₃₃H₂₉O₃P 
• 1579996-94-3 (S)-2,5-diphenyl-4-hydroxyphenyl phenyl(2,4,6-trimethylphenyl)phosphinite 
• 217975-66-1 phenyl(2,4,6-trimethyl)phosphine 
• 2633-66-1 2-mesitylmagnesium bromide 
• 644-97-3 Dichlorophenylphosphine 
• 142087-69-2 P-phenyl-P-2,4,6-trimethylphenylphosphinic acid 
• 4073-31-8 (diethylamino)phenylchlorophosphine 
• 142087-74-9 (1R)-N-(1-phenylethyl)-(R_P)-P-phenyl-P-(2,4,6-trimethylphenyl) phosphinamide 

Relevant academic research and scientific papers

Asymmetric synthesis of P -stereogenic diarylphosphinites by palladium-catalyzed enantioselective addition of diarylphosphines to benzoquinones

The reaction of phenyl(2,4,6-trimethylphenyl)phosphine with a substituted benzoquinone in the presence of a chiral phosphapalladacycle complex as a catalyst and triethylamine in chloroform at -45 °C proceeded in a new type of addition manner to give a high yield of a 4-hydroxyphenyl phenyl(2,4,6-trimethylphenyl)phosphinite with 98% enantioselectivity, which is a versatile intermediate readily convertible into various phosphines and their derivatives with high enantiomeric purity.

Stereoselective reactions of optically active derivatives of α-methylbenzylaminophosphine

A number of N-(α-methylbenzyl) phosphorus amides were synthesized, and their stereochemical properties were studied. Reactions of achiral chlorophosphines with optically active α-methylbenzylamine are accompanied by asymmetric induction at the phosphorus

The Synthesis of Optically Active P-Phenyl-P-(2,4,6-trimethylphenyl)phosphinamide and an X-Ray Structure of (-)-(1R)-N-(1-Phenylethyl)-(SP)-P-phenyl-P-(2,4,6-trimethylphenyl)phosphinamide

The primary phosphinic amide P-phenyl-P-(2,4,6-trimethylphenyl)phosphinamide has been prepared in optically active form (75percent enantiomeric excess) in six steps from dichlorophenylphosphine.The configuration of the intermediate N-(1-phenylethyl)-P-phenyl-P-(2,4,6-trimethylphenyl)phosphinamide has been established by an X-ray crystal structure determination of the minor diastereoisomer.This compound exhibits in the solid state two independent rotameric conformations about the P-N bond.Geometry optimisation by MNDO MO calculations refined these to the same rotamer having the nitrogen lone pair anticlinal to the P-O bond.