1421260-41-4

Basic information

• Product Name: N,N-dimethyl-2-methyl-3-(3-hydroxyphenyl)valeramide
• Synonyms: N,N-dimethyl-2-methyl-3-(3-hydroxyphenyl)valeramide
• CAS NO: 1421260-41-4
• Molecular Weight: 235.326
• Mol File: 1421260-41-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 384.8±25.0 °C(Predicted)
• Density: 1.044±0.06 g/cm3(Predicted)
• CAS DataBase Reference: N,N-dimethyl-2-methyl-3-(3-hydroxyphenyl)valeramide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2-methyl-3-(3-hydroxyphenyl)valeramide(1421260-41-4)
• EPA Substance Registry System: N,N-dimethyl-2-methyl-3-(3-hydroxyphenyl)valeramide(1421260-41-4)

Safety Data

• Hazardous Substances Data: 1421260-41-4(Hazardous Substances Data)

Upstream product

• 1313429-30-9 2-methyl-3-(3-methoxyphenyl)valeryl chloride 
• 1313374-17-2 N,N-dimethyl-2-methyl-3-(3-methoxyphenyl)valeramide 
• 1313429-26-3 diethyl 1-(3-methoxyphenyl)propylmethylmalonate 
• 1313429-17-2 3-(1-bromopropyl)anisole 
• 1616-70-2 2-methyl-3-(3-methoxyphenyl)valeric acid 

Downstream Products

• 175591-23-8 tapentadol 
• 175591-09-0 tapentadol hydrochloride 
• 175591-10-3 (+)-(1S,2S)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol hydrochloride 
• 175591-09-0 3-[(2R,3S)-1-(dimethylamino)-2-methylpentan-3-yl]phenol hydrochloride 
• 1282502-23-1 (2S,3R)-3-(3-hydroxyphenyl)-N,N,2-trimethylpentan-1-aminium chloride 

Relevant articles and documents

Novel Intermediate Used for Preparing Tapentadol or Analogues Thereof

The invention discloses a novel intermediate for preparing tapentadol and analogues thereof, wherein the structural formula is shown as formula I or II, and the groups are defined as the specification. The invention further discloses a method for preparing the novel intermediate and use of the intermediate for preparing tapentadol and analogues thereof. The invention can remarkably improve the product yield and quality of tapentadol, reduce the production cost, and simplify the production procedure. The preparation process is environment friendly, thus more suitable for the requirements of industrial production.