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2-(methylthio)-N-(3-(2-oxopyrrolidin-1-yl)propyl)-4-(phenylamino)pyrimidine-5-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1421367-68-1

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  • 2-(methylthio)-N-(3-(2-oxopyrrolidin-1-yl)propyl)-4-(phenylamino)pyrimidine-5-carboxamide

    Cas No: 1421367-68-1

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1421367-68-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1421367-68-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,3,6 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1421367-68:
(9*1)+(8*4)+(7*2)+(6*1)+(5*3)+(4*6)+(3*7)+(2*6)+(1*8)=141
141 % 10 = 1
So 1421367-68-1 is a valid CAS Registry Number.

1421367-68-1Relevant articles and documents

Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase

Aydogan, Yagmur,Berger, Benedict-Tilman,Chaikuad, Apirat,Drewry, David H.,Knapp, Stefan,Müller, Susanne,Mandel, Sebastian,Mauer, Sandy,Pohl, Christian,Russ, Nadine,Schr?der, Martin

, p. 14358 - 14376 (2021/10/12)

CASK (Ca2+/calmodulin-dependent Ser/Thr kinase) is a member of the MAGUK (membrane-associated guanylate kinase) family that functions as neurexin kinases with roles implicated in neuronal synapses and trafficking. The lack of a canonical DFG motif, which

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Powell, Noel A.,Hoffman, Jennifer K.,Ciske, Fred L.,Kaufman, Michael D.,Kohrt, Jeffrey T.,Quin III, John,Sheehan, Derek J.,Delaney, Amy,Baxi, Sangita M.,Catana, Cornel,McConnell, Patrick,Ohren, Jeff,Perrin, Lisa A.,Edmunds, Jeremy J.

, p. 1046 - 1050 (2013/03/14)

We report the SAR around a series of 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. 2-Aminophenethyl analogs demonstrate excellent potency but moderate kinase selectivity, while 2-aminobenzyl analogs that fill the Ala571 subpocket exhibit good inhibition activity and excellent kinase selectivity.

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