1421375-92-9

Upstream product

• 627531-48-0 N-(3-chloro-4-cyano-2-methylphenyl)acetamide 
• 573768-09-9 4-amino-2-chloro-3-methyl-benzonitrile 
• 757247-75-9 2-chloro-4-iodo-3-methylbenzonitrile 
• 1297544-91-2 2-chloro-4-formyl-3-methylbenzonitrile 
• 4298-08-2 trans-3-hydroxy-L-proline 
• 496841-04-4 methyl (2S,3S)-3-hydroxypyrrolidine-2-carboxylate 
• 1421375-76-9 (2S,3S)-methyl 3-hydroxy-1-nitrosopyrrolidine-2-carboxylate 
• 1421375-77-0 (2S,3S)-methyl 3-(tert-butyldimethylsilyloxy)-1-nitrosopyrrolidine-2-carboxylate 
• 1421375-78-1 ((2R,3S)-3-(tert-butyldimethylsilyloxy)-1-nitrosopyrrolidin-2-yl)methanol 
• 1421375-79-2 ((2R,3S)-1-amino-3-(tert-butyldimethylsilyloxy)pyrrolidin-2-yl)methanol 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 1421375-83-8 4-((E)-((2R,3S)-3-(tert-butyldimethylsilyloxy)-2-(hydroxymethyl)pyrrolidin-1-ylimino)methyl)-2-chloro-3-methylbenzonitrile 
• 1421375-85-0 4-((E)-((2R,3S)-3-(tert-butyldimethylsilyloxy)-2-formylpyrrolidin-1-ylimino)methyl)-2-chloro-3-methylbenzonitrile 
• 1421375-87-2 4-((3S,3aR,4S)-4-(tert-butyldimethylsilyloxy)-3-hydroxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl)-2-chloro-3-methylbenzonitrile 

Downstream Products

• 1421375-93-0 (3S,3aS,4R)-2-(3-chloro-4-cyano-2-methylphenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-4-yl benzoate 
• 1421375-29-2 2-chloro-4-((3S,3aS,4R)-3,4-dihydroxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl)-3-methylbenzonitrile 
• 1421375-94-1 2-chloro-4-((3S,3aS,4R)-4-hydroxy-3-(tetrahydro-2H-pyran-2-yloxy)-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl)-3-methylbenzonitrile 

Relevant academic research and scientific papers

PYRAZOLINE DERIVATIVES AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I), in which the substituents are as defined in the specification; to compounds of formula (I) for use as androgen receptor modulators. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

PYRAZOLINE DERIVATIVES AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I), in which the substituents are as defined in the specification; to compounds of formula (I) for use as androgen receptor modulators. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition