1213770-27-4 Usage
General Description
(2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole is a chemical compound with the molecular formula C28H41NO2Si. It is an octahydro-1H-indole derivative with a diphenylmethyl group and a trimethylsilyloxy group attached to the carbon atom. (2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole is commonly used in organic synthesis and pharmaceutical research as a building block for the development of novel drugs and biologically active molecules. Its unique structure and functional groups make it a valuable intermediate for the synthesis of various complex compounds, and it has potential applications in medicinal chemistry and drug discovery. The specific properties and potential biological activities of this compound have not been extensively studied, but its structural features suggest that it may have interesting pharmacological and biological properties worth exploring.
Check Digit Verification of cas no
The CAS Registry Mumber 1213770-27-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,7,7 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1213770-27:
(9*1)+(8*2)+(7*1)+(6*3)+(5*7)+(4*7)+(3*0)+(2*2)+(1*7)=124
124 % 10 = 4
So 1213770-27-4 is a valid CAS Registry Number.
1213770-27-4Relevant articles and documents
Organocatalyzed regioselective and enantioselective synthesis of 1,4- and 1,2-dihydropyridines
Le, Truong-Giang,Pham, Hoai-Thu,Martin, James P.,Chataigner, Isabelle,Renaud, Jean-Luc
supporting information, p. 2673 - 2684 (2020/08/07)
Herein, we introduce one of the first examples of asymmetric organocatalyzed synthesis of 1,2-dihydropyridines, affording enantioselective access to and partially solving regioselectivity challenges in the synthesis of dihydropyridines. We demonstrate that through modification of organocatalysts both 1,2- and 1,4-dihydropyridines (1,2- and 1,4-DHPs) can be obtained with high regioselectivity (ratio of 1,2-DHP/1,4-DHP from 95/5 to 0/100) and enantioselectivity (33% ee for 1,2-DHPs and up to 98% ee for 1,4-DHPs) in good yields (up to 87%).
