1421605-72-2Relevant academic research and scientific papers
3-Phenacylideneoxindoles with tosylmethyl isocyanide and MeOH through C-C bond cleavage: Facile synthesis of pyrrole and 2H-pyrrolo[3,4-c]quinoline derivatives
Wang, Rong,Xu, Xiao-Ping,Meng, Hua,Wang, Shun-Yi,Ji, Shun-Jun
, p. 1761 - 1766 (2013/03/14)
A novel reaction of 3-phenacylideneoxindoles (1) with tosylmethyl isocyanide (2a) and MeOH through C-C bond cleavage has been developed. The reaction proceeded under mild conditions, providing a powerful synthetic tool for the construction of pyrrole derivatives (3) from easily accessible starting materials and synthesis of 2H-pyrrolo[3,4-c]quinolines (4) by further dehydration of 3.
