1421844-90-7Relevant academic research and scientific papers
Efficient synthesis of 3,3′-bisindoles catalyzed by Fe3O4@MCM-48-OSO3H magnetic core-shell nanoparticles
Khorshidi, Alireza,Shariati, Shahab
, p. 778 - 784 (2015)
Magnetite nanoparticles coated with sulfuric acid-functionalized mesoporous MCM-48 were synthesized and used as a catalyst in three-component domino reactions of indoles, arylglyoxal monohydrates and N-arylenaminones to furnish the desired 3,3′-bisindoles by formation of two C-C and one C-N bonds in a smooth cascade with good yields under mild reaction conditions. The catalyst was recovered easily and maintained activity in successive runs.
Three-component domino reactions for regioselective formation of bis-indole derivatives
Fu, Li-Ping,Shi, Qing-Qing,Shi, Yu,Jiang, Bo,Tu, Shu-Jiang
supporting information, p. 135 - 140 (2013/03/14)
A microwave-assisted regioselective reaction dealing with arylglyoxal monohydrate, diverse N-aryl enaminones, and indoles to achieve 3,2′- and 3,3′-bis-indoles by varying a substituted indole substrate is reported. The 2-unsubstituted indoles resulted in the 3,2′-bis-indole skeleton, whereas indoles bearing a methyl or phenyl group at C2 led to the 3,3′-bis-indoles with simultaneous formation of three sigma-bonds. The procedures feature excellent regioselectivity, short reaction times, convenient one-pot manner, and operational simplicity.
