1421864-49-4Relevant academic research and scientific papers
Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)
Qian, Wen-Jian,Park, Jung-Eun,Lee, Kyung S.,Burke Jr., Terrence R.
supporting information, p. 7306 - 7308 (2013/02/22)
We report herein that incorporating long-chain alkylphenyl-containing non-proteinogenic amino acids in place of His at the pT-2 position of the parent polo-like kinase 1 (Plk1) polo box domain (PBD)-binding pentapeptide, PLHSpT (1a) increases affinity. Fo
