1422008-22-7Relevant academic research and scientific papers
Preparation method and applications of aromatic heterocyclic compound adopted as selective JAK3 and/or JAK1 kinase inhibitor
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Paragraph 0145-0148; 0277-0280, (2016/10/08)
The present invention relates to an aromatic heterocyclic compound, a preparation method and applications thereof, wherein the structure of the compound is represented by a general formula (I), each group is defined in the specification, and the compound
Pd-catalyzed thiocarbonylation with stoichiometric carbon monoxide: Scope and applications
Burhardt, Mia N.,Taaning, Rolf H.,Skrydstrup, Troels
, p. 948 - 951 (2013/03/28)
A general protocol for the Pd-catalyzed thiocarbonylation of aryl iodides with stoichiometric carbon monoxide has been established employing a catalytic system composed of Pd(OAc)2 and DPEphos with low catalyst loading (1 mol %). Both electron-rich and -deficient aryl iodides proved effective for these couplings with aryl and alkyl thiols. The choice of the metal ligands and the solvent system was crucial for the efficiency and chemoselectivity of these transformations.
