1422378-46-8

Basic information

• Product Name: C₁₇H₁₅BrN₂
• Synonyms: C₁₇H₁₅BrN₂
• CAS NO: 1422378-46-8
• Molecular Weight: 327.224
• Mol File: 1422378-46-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₅BrN₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₅BrN₂(1422378-46-8)
• EPA Substance Registry System: C₁₇H₁₅BrN₂(1422378-46-8)

Safety Data

• Hazardous Substances Data: 1422378-46-8(Hazardous Substances Data)

Upstream product

• 583-68-6 2-bromo-p-toluidine 
• 106-49-0 p-toluidine 
• 84839-95-2 6-methyl-8-bromoquinoline 
• 1422378-38-8 C₁₇H₁₆N₂ 

Relevant articles and documents

Catalytic dehydrogenative borylation of terminal alkynes by a SiNN pincer complex of iridium

Compounds with carbon-boron bonds are versatile intermediates for building more complex molecules via the elaboration of the carbon-boron bonds into other carbon-element bonds. The synthesis of carbon-boron bonds by catalytic dehydrogenative borylation of carbon-hydrogen bonds with dialkoxyboranes (RO)2BH is particularly attractive. It has been demonstrated for a variety of carbon-hydrogen bond types but not for the C(sp)-H bonds of terminal alkynes, for which hydroboration of the triple bond is a competing process. We report a new iridium catalyst that is strictly chemoselective for C-H borylation of terminal alkynes. The key to the success of this catalyst appears to be the new ancillary SiNN pincer ligand that combines amido, quinoline, and silyl donors and gives rise to structurally unusual Ir complexes. A variety of terminal alkynes (RC≡C-H) can be converted to their alkynylboronates (RC≡C-Bpin, where pin = pinacolate) in high yield and purity within minutes at ambient temperature.