1422570-82-8

Basic information

• Product Name: 4-(5-(3,5-dibromo-4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride
• Synonyms: 4-(5-(3,5-dibromo-4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride
• CAS NO: 1422570-82-8
• Molecular Weight: 492.12
• Mol File: 1422570-82-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(5-(3,5-dibromo-4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-(3,5-dibromo-4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride(1422570-82-8)
• EPA Substance Registry System: 4-(5-(3,5-dibromo-4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride(1422570-82-8)

Safety Data

• Hazardous Substances Data: 1422570-82-8(Hazardous Substances Data)

Upstream product

• 4073-35-2 3,5-dibromo-4-methoxybenzoic acid 
• 340216-49-1 3,5-dibromo-4-methoxybenzohydrazide 
• 150-13-0 4-amino-benzoic acid 
• 455-26-5 4-carboxybenzenesulfonyl fluoride 
• 3337-62-0 3,5-dibromo-4-hydroxybenzoic acid 
• 22812-61-9 methyl 3,5-dibromo-4-methoxybenzoate 
• 402-55-1 4-fluorosulfonylbenzoyl chloride 
• 65-85-0 benzoic acid 
• 10130-89-9 p-carboxyphenylsulfonyl chloride 

Downstream Products

• 1422570-01-1 3-(5-(3,5-dibromo-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride 
• 1422570-37-3 4-(5-(3,5-dibromo-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl fluoride 

Relevant articles and documents

Copper-free Sandmeyer-type Reaction for the Synthesis of Sulfonyl Fluorides

A copper-free Sandmeyer-type fluorosulfonylation reaction is reported. Utilizing Na2S2O5 and Selectfluor as the sulfur dioxide and fluorine sources, respectively, aryldiazonium salts were transformed into sulfonyl fluorides. The one-pot direct synthesis of sulfonyl fluorides from aromatic amines was also realized via in situ diazotization. The practicality of this method was demonstrated by the broad functional group tolerance, gram-scale synthesis, and late-stage fluorosulfonylation of natural products and pharmaceuticals.