4073-35-2

Usage

Uses

Used in Pharmaceutical Development:
3,5-Dibromo-4-methoxybenzoic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, which includes the bromine atoms and methoxy group, allows for the creation of new drug molecules with potential therapeutic applications.
Used in Specialty Chemical Applications:
In the chemical industry, 3,5-dibromo-4-methoxybenzoic acid is used as a building block for the development of specialty chemicals. Its properties, such as the presence of bromine and the methoxy group, make it a valuable component in the synthesis of complex molecules with specific functions and properties.
Used in Academic Research:
3,5-Dibromo-4-methoxybenzoic acid is employed as a research compound in academic settings, where scientists study its chemical properties, reactivity, and potential applications in various fields, including materials science, organic chemistry, and medicinal chemistry. This research can lead to the discovery of new compounds and applications that can benefit various industries.

InChI:InChI=1/C8H6Br2O3/c1-13-7-5(9)2-4(8(11)12)3-6(7)10/h2-3H,1H3,(H,11,12)

Upstream product

• 22812-61-9 methyl 3,5-dibromo-4-methoxybenzoate 
• 3337-62-0 3,5-dibromo-4-hydroxybenzoic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-09-4 4-methoxybenzoic acid 
• 79324-79-1 1-(3,5-dibromo-4-methoxyphenyl)ethanone 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 7732-18-5 water 
• 7697-37-2 nitric acid 
• 854692-55-0 2-bromo-1-(3,5-dibromo-4-methoxy-phenyl)-propan-1-one 
• 41727-47-3 methyl 3,5-dibromo-4-hydroxybenzoate 

Downstream Products

• 122136-05-4 3,5-dibromo-4-methoxy-benzoic acid ethyl ester 
• 31106-74-8 1,3-dibromo-2-methoxy-5-nitrobenzene 
• 3337-62-0 3,5-dibromo-4-hydroxybenzoic acid 
• 101081-38-3 bis-(3,5-dibromo-4-methoxy-benzoyl)-peroxide 
• 615-58-7 2,4-dibromophenol 
• 95-56-7 2-hydroxybromobenzene 
• 608-33-3 2,6-dibromophenol 
• 488-48-2 tetrabromobenzoquinone 
• 607-99-8 2,4,6-tribromoanisole 
• 4319-02-2 4-O-methylgallic acid 
• 120-80-9 benzene-1,2-diol 
• 108-95-2 phenol 
• 1414518-14-1 (Z)-5-(3-bromo-4-hydroxybenzylidene)-4-(3-bromo-4-hydroxyphenyl)-3-(3,5-dibromo-4-hydroxybenzoyl)furan-2(5H)-one 

Relevant academic research and scientific papers

Alkaloid pulmonarin B derivative and its synthesis and application in the prevention and control of plant viruses and mycosis

The present invention relates to a class of alkaloids pulmonarin B derivatives thereof and their synthesis and application in the control of plant viruses and mycosis. The present invention is based on systematic research literature, combined with the exp

A convenient and efficient H2SO4-promoted regioselective monobromination of phenol derivatives using N-bromosuccinimide

A convenient, rapid H2SO4-promoted regioselective monobromination reaction with N-bromosuccinimide was developed. The desired para-monobrominated or ortho-monobrominated products of phenol derivatives were obtained in good to excellent yields with high selectivity. Regioselective chlorination and iodination were also achieved in the presence of H2SO4 using N-chlorosuccinimide and N-iodosuccinimide, respectively.

N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY

Novel N-hydroxyamide derivatives are disclosed. These N-hydroxyamide derivatives inhibit UPD-3O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.

Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia

This invention provides compounds of Formula I having the structure E is S, SO, SO2, O, or NR1c; X is hydrogen, halogen, alkyl of 1-6 carbon atoms, alkenyl of 2-7 carbon atoms, CN, aryl, aralkyl of 6-12 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, hydroxyaralkyl of 6-12 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, aryloxy; arylalkoxy, nitro, amino, NR2R2a, NR2COR2a, cycloalkylamino of 3-8 carbon atoms, morpholino, alkylsulfanyl of 1-6 carbon atoms, arylsulfanyl, pyridylsulfanyl, 2-N,N-dimethylaminoethylsulfanyl, —OCH2CO2R2bor —COR2c; Z1and Z2are each, independently, hydrogen, halogen, CN, alkyl of 1-6 carbon atoms, aryl, aralkyl of 6-12 carbon atoms, cycloalkyl of 3-8 carbon atoms, nitro, amino, —NR1R1a, —NR1COR1a, cycloalkylamino of 3-8 carbon atoms, morpholino, or OR8, or Z1and Z2may be taken together as a diene unit having the formula —CH═CR9—CR10═CR11—; or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

Steric Enhancement of Resonance-Evidence from Kinetic Study on some Acetophenones

The kinetics of oxidation of some mono-, di- and tri-substituted acetophenones by alkaline hexacyanoferrate(III) in 50percent (v/v) methanol-water mixture at constant ionic strength and at 20, 30 and 40 deg have been studied spectrophotometrically and the rate constants determined by least-squares analysis.Electron-withdrawing groups in the ring facilitate the oxidation of the acetyl function while electron-releasing groups retard the rate.The rate constant values for the oxidation of 3-substituted-4-alkoxy-acetophenones are computed based on the principle of additivity of group effects.The observed rate constants are significantly lower than the calculated values.This is attributed to the phenomenon of steric enhancement of resonance (SER). 3,5-Disubstituted-4-methoxyacetophenones have higher observed rate constant values than the calculated ones.The steric inhibition of resonance (SIR) operates in these systems.In the case of 3-halogeno-4-methoxyacetophenones, the importance of SER increases with increase in the bulkiness of the 3-substituents.The difference between the calculated and observed multiple substituent constants of 3-substituted-4-methoxyacetophenones also lends support for SER.