1422958-91-5 Usage
Uses
Used in Oncology:
C42H38N2O9 is used as a chemotherapeutic agent for the treatment of various types of cancer, including lung cancer, testicular cancer, and lymphomas. Its topoisomerase II inhibitory activity prevents DNA replication, leading to cell death in cancer cells and providing a therapeutic advantage in cancer treatment.
Used in Combination Therapy:
In the field of oncology, C42H38N2O9 is used as a component of combination therapy with other chemotherapeutic drugs. This approach aims to enhance the overall therapeutic effects and improve patient outcomes by leveraging the synergistic action of multiple drugs against cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 1422958-91-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,2,9,5 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1422958-91:
(9*1)+(8*4)+(7*2)+(6*2)+(5*9)+(4*5)+(3*8)+(2*9)+(1*1)=175
175 % 10 = 5
So 1422958-91-5 is a valid CAS Registry Number.
1422958-91-5Relevant academic research and scientific papers
Synthesis of 4-aminophthalimide and 2,4-diaminopyrimidine C-nucleosides as isosteric fluorescent DNA base substitutes
Weinberger, Michael,Berndt, Falko,Mahrwald, Rainer,Ernsting, Nikolaus P.,Wagenknecht, Hans-Achim
, p. 2589 - 2599 (2013/04/24)
The 4-aminophthalimide C-nucleoside 1 was designed as an isosteric DNA base surrogate, and a synthetic route to nucleoside 1 together with the 2,4-diaminopyrimidine-C-nucleoside 2 as a potential counterbase was worked out. The key steps in both synthetic
