1423122-42-2Relevant articles and documents
Synthesis of azahomosteroid ring system through intramolecular [4+2] cycloaddition of in situ generated azaisobenzofuran intermediates
Roy, Priyabrata,Mitra, Partha,Ghorai, Binay Krishna
, p. 1440 - 1443 (2013/04/24)
Azahomosteroid ring systems were synthesized through two-component coupling of γ,δ-unsaturated Fischer carbene complexes with o-alkynylheteroaryl carbonyl derivatives. The reaction occurs through the formation of azaisobenzofuran as transient intermediate; the latter undergoes a subsequent Diels-Alder cycloaddition reaction with in-built dienophile with high regio- and stereoselectivity. Copyright