142386-46-7

Upstream product

• 951165-32-5 6,6'-di-O-tert-butyldimethylsilyl-2,3,4,2',3',4'-hexa-O-benzoyl-α,α-D-trehalose 
• 99-20-7 TREHALOSE 
• 98-88-4 benzoyl chloride 
• 142386-45-6 2,3,4,2',3',4'-hexa-O-benzoyl-6,6'-di-O-triphenylmethyl-α,α-trehalose 

Downstream Products

• 951165-33-6 6,6'-di-O-phenoxythiocarbonyl-2,3,4,2',3',4'-hexa-O-benzoyl-α,α-D-trehalose 
• 146530-69-0 O-(2,3,4-tri-O-benzoyl-α-D-glucopyranosyl)-(1<*>1)-2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside 
• 243132-04-9 2,3,4,2',3',4'-hexa-O-benzoyl-6,6'-dicyano-6,6'-dideoxy-α,α-trehalose 
• 243132-09-4 (R)-2,3,4,2',3',4'-hexa-O-benzoyl-6,6'-dideoxy-6,6'-bis[1-(hydroxymethyl)propylamino]-α,α-trehalose 
• 243132-08-3 (S)-2,3,4,2',3',4'-hexa-O-benzoyl-6,6'-dideoxy-6,6'-bis[1-(hydroxymethyl)propylamino]-α,α-trehalose 
• 18933-87-4 6,6'-diazido-2,2',3,3',4,4'-hexa-O-benzoyl-6,6'-dideoxy-α,α-D-trehalose 
• 577969-92-7 2,2',3,3',4,4'-hexa-O-benzoyl-6,6'-dideoxy-α,α-trehalose 
• 951165-34-7 2,3,4,6,2',3',4'-hepta-O-benzoyl-6'-O-phenoxythiocarbonyl-α,α-D-trehalose 
• 142386-47-8 2,2',3,3',4,4'-hexa-O-benzoyl-6,6'-bis-O-((trifluoromethyl)sulfonyl)-α,α'-trehalose 

Relevant academic research and scientific papers

DIARYL TREHALOSE COMPOUNDS AND USES THEREOF

Disclosed herein are diaryl trehalose compounds and methods of use thereof, for example as vaccine adjuvants.

Synthesis of mono- and dideoxygenated α,α-trehalose analogs

In this work, we describe the synthesis and NMR characterization of four mono- and four dideoxygenated analogs of α,α-d-trehalose. The symmetrical (2,2′-, 3,3′-, 4,4′- and 6,6′-) dideoxy analogs were obtained via selective protection and subsequent radica

Ethambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis

Ethambutol is an established front-line agent for the treatment of tuberculosis, and is also active against Mycobacterium avium infection. However, this agent exhibits toxicity, and is considered to have low potency. The action of ethambutol on the mycoba

Use of diphenylacetyl chloride as protective reagent for sugars

Diphenylacetyl chloride is used as a protective reagent for methyl α-D-glucopyranoside, methyl α-D-mannopyranoside, and α,α-trehalose showing a good regioselectivity. The obtained diphenylacetyl esters were readily removed under neutral and mild conditions with N-bromosuccinimide followed by thiourea, in a one-pot reaction, in the presence of acetyl or benzoyl groups.

Glycophanes, cyclodextrin-cyclophane hybrid receptors for apolar binding in aqueous solutions. A stereoselective carbohydrate-carbohydrate interaction in water

The synthesis and complexing properties of a new type of neutral chiral receptors, glycophanes 4-6 and 9-14, are reported. They may be considered as cyclodextrin-cyclophane hybrids because carbohydrate molecules, lipophilic cavities, and aromatic interact

A Novel Class of Neutral Chiral Cyclophanes from α,α'-Trehalose

The synthesis and preliminary complexation studies of a new class of chiral cyclophanes 1-6, with properties comparable to cyclodextrins and cyclophanes, is described.