1424336-84-4

Basic information

• Product Name: C₂₇H₃₃FN₄O₇S
• Synonyms: C₂₇H₃₃FN₄O₇S
• CAS NO: 1424336-84-4
• Molecular Weight: 576.646
• Mol File: 1424336-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₃FN₄O₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₃FN₄O₇S(1424336-84-4)
• EPA Substance Registry System: C₂₇H₃₃FN₄O₇S(1424336-84-4)

Safety Data

• Hazardous Substances Data: 1424336-84-4(Hazardous Substances Data)

Upstream product

• 27631-29-4 2-chloro-6,7-dimethoxy-3H-quinazolin-4-one 
• 1424336-77-5 2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 832755-13-2 2-fluoro-4-methanesulfonylaniline 

Relevant articles and documents

Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists

GPR119 agonist has emerged as a promising target for the treatment of type 2 diabetes. A series of novel 2,4-disubstituted quinazoline analogues was prepared and evaluated their agonistic activity against human GPR119. The analogues bearing azabicyclic amine substituents (12a, 12c and 12g) exhibited better EC50 values than that of OEA though they appeared to be partial agonists.