1425044-76-3Relevant academic research and scientific papers
PI3 KINASE INHIBITORS AND USES THEREOF
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Paragraph 00224, (2019/02/15)
Described herein are PI3 Kinase inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, cardiovascular diseases, and inflammatory diseases.
SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE
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Paragraph 0366, (2016/09/22)
The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the a
SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE
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Paragraph 0722; 0723; 0724, (2015/03/31)
The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the activity of the PI3K enzymes. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of disorders or diseases, such as disorders of immunity and inflammation in which PI3K enzymes play a role in leukocyte function, and hyperproliferative disorders associated with PI3K activity, including but not restricted to leukemias and solid tumors, in mammals, especially humans.
HETEROCYCLIC COMPOUNDS AND USES THEREOF
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, (2013/10/22)
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
