142604-13-5

Basic information

• Product Name: Carbamic acid, [2-[(2-hydroxyethyl)sulfonyl]ethyl]-, 1,1-dimethylethyl ester
• Synonyms: 2-(2-tert-butoxycarbonylaminoethanesulfonyl)ethanol;tert-butyl {2-[(2-hydroxyethyl)sulfonyl]ethyl}carbamate;tert-butyl-2-(2-hydroxyethylsulfonyl)ethylcarbamate;2-<<(N-t-Boc)-2-aminoethyl>sulphonyl>ethanol;[2-(2-Hydroxy-ethanesulfonyl)-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 142604-13-5
• Molecular Formula: C9H19NO5S
• Molecular Weight: 253.31600
• Mol File: 142604-13-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[(2-hydroxyethyl)sulfonyl]ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[(2-hydroxyethyl)sulfonyl]ethyl]-, 1,1-dimethylethyl ester(142604-13-5)
• EPA Substance Registry System: Carbamic acid, [2-[(2-hydroxyethyl)sulfonyl]ethyl]-, 1,1-dimethylethyl ester(142604-13-5)

Safety Data

• Hazardous Substances Data: 142604-13-5(Hazardous Substances Data)

Upstream product

• 158690-56-3 2-(tert-butoxycarbonylamino)ethyl-4-methylbenzenesulfonate 
• 26690-80-2 2-(N-tert-butoxycarbonylamino)ethanol 
• 67385-10-8 di-tert-butyl(disulfanediylbis(ethane-2,1-diyl))dicarbamate 
• 67385-09-5 2-[(tert-butoxycarbonyl)amino]-1-ethanethiol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75937-17-6 2->mercaptoethanol 

Downstream Products

• 86677-26-1 sulfuric acid mono[2-(2-amino-ethanesulfonyl)-ethyl] ester 

Relevant articles and documents

Synthesis of a versatile purification handle for use with Boc chemistry solid phase peptide synthesis

The synthesis of a versatile handle for the purification of synthetic peptides is described. The Boc-aminoethylsulfonylethyloxycarbonyl handle is coupled to the NH2-terminus of the resin-bound peptide. Removal of the Boc group affords a free amine which can be derivatized with any of a variety of functionalities. Cleavage from the resin gives a peptide functionalized for covalent chemoselective reaction with the column support. Desired full length peptide is eluted from the column by cleavage of the handle by treatment with base.

SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

A novel synthesis of sulfuric acid mono-[2-(2-amino-ethanesulfonyl)-ethyl] ester for use as an intermediate in the preparation of reactive dyes

Sulfuric acid mono-[2-(2-amino-ethanesulfonyl)-ethyl] ester 8, which is a key intermediate of reactive dyes was prepared in four steps in good overall yield under mild conditions from 2-aminoethanethiol and 2-bromoethanol.