75937-17-6Relevant academic research and scientific papers
ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF
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Page/Page column 59-60, (2021/06/26)
The present invention relates to a compound represented by the following formula (I): A[B-(C)v]w, wherein A is a photoprotective moiety, B is a linker, C is a functional group, v is an integer from 1 to 2000, and w is an integer from
SERINE/THREONINE KINASE INHIBITORS
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Paragraph 0377, (2015/02/19)
Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
FUSED HETEROCYCLIC COMPOUND
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Page/Page column 256-257, (2010/11/28)
A compound of the formula: wherein ring'' A is a 7-membered or 8-membered nitrogen- containing ring optionally further substituted, ring B is an optionally substituted aryl group or an optionally substituted heteroaryl group, X1 is a group represented by -NR3-Y1-, -0-, -S-, -SO-, -SO2- or -CHR3- wherein R3 is a hydrogen atom or'' an optionally substituted aliphatic hydrocarbon group, or R3 may be bonded to the carbon atom of ring B to form an optionally substituted ring structure, and Y1 is a bond or an optionally substituted C1-4 alkylene, R1 is a hydrogen atom, or an optionally substituted group bonded via a carbon atom or a sulfur atom, the formula = shows a single bond or a double bond, when ===R2 is - R2, R2 is a hydrogen atom, or an optionally substituted group bonded via a carbon atom, a nitrogen atom, an oxygen atom or a sulfur atom, and when ===R2 is =R2, R2 is an oxo group, an optionally substituted alkylidene group, or an optionally, substituted imino group.
A novel synthesis of sulfuric acid mono-[2-(2-amino-ethanesulfonyl)-ethyl] ester for use as an intermediate in the preparation of reactive dyes
Kim, Young Zu,Kim, Jae Pil
, p. 1601 - 1605 (2007/10/03)
Sulfuric acid mono-[2-(2-amino-ethanesulfonyl)-ethyl] ester 8, which is a key intermediate of reactive dyes was prepared in four steps in good overall yield under mild conditions from 2-aminoethanethiol and 2-bromoethanol.
An N-terminal method for peptide solubilisation
Englebretsen, Darren R.,Robillard, George T.
, p. 6623 - 6634 (2007/10/03)
Peptide-constructs of the form (solubilising peptide)- [NH(CH2)2SO2(CH2)2O-CO]-(insoluble peptide) were synthesised by Boc SPPS. The HPLC-purified peptide-constructs were cleaved with aqueous base to liberate the insoluble peptides as precipitates.
Synthesis of a versatile purification handle for use with Boc chemistry solid phase peptide synthesis
Canne, Lynne E.,Winston, Rachel L.,Kent, Stephen B. H.
, p. 3361 - 3364 (2007/10/03)
The synthesis of a versatile handle for the purification of synthetic peptides is described. The Boc-aminoethylsulfonylethyloxycarbonyl handle is coupled to the NH2-terminus of the resin-bound peptide. Removal of the Boc group affords a free amine which can be derivatized with any of a variety of functionalities. Cleavage from the resin gives a peptide functionalized for covalent chemoselective reaction with the column support. Desired full length peptide is eluted from the column by cleavage of the handle by treatment with base.
