1426214-86-9

Basic information

• Product Name: N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-cyano-5-methylbenzenesulfonamide
• Synonyms: N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-cyano-5-methylbenzenesulfonamide
• CAS NO: 1426214-86-9
• Molecular Weight: 405.44
• Mol File: 1426214-86-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-cyano-5-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-cyano-5-methylbenzenesulfonamide(1426214-86-9)
• EPA Substance Registry System: N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-cyano-5-methylbenzenesulfonamide(1426214-86-9)

Safety Data

• Hazardous Substances Data: 1426214-86-9(Hazardous Substances Data)

Upstream product

• 1426214-89-2 [4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-carbamic acid tert-butyl ester 
• 330793-01-6 (4-tert-butoxycarbonylaminophenyl)boronic acid pinacol ester 
• 1426215-67-9 C₁₁H₁₀N₆ 
• 197960-31-9 2-cyano-5-methylbenzene-1-sulfonyl chloride 
• 76-05-1 trifluoroacetic acid 
• 1426214-88-1 [4-(6-chloro-5-cyanopyrazine-2-yl)phenyl]aminoformic acid tert-butyl ester 
• 313339-92-3 3,5-dichloro-pyrazine-2-carbonitrile 

Relevant articles and documents

N-[ 4-(1H-pypazolo [3, 4-b] aminopyrazine-6-yl)-phenyl]-and its use as a chemical acylsulfonamide

PROBLEM TO BE SOLVED: To provide a compound effective for the treatment of diseases due to the inadequacy of serum and glucocorticoid adjustment kinase (SGK) activities, for instance, degenerative arthropathy or inflammatory process, e.g., osteoarthritis or rheumatism, to provide its use as a drug, and to provide a pharmaceutical composition containing the same. SOLUTION: The compound is represented by formula I ( wherein, Ar is selected from the group consisting of phenyl and five- or six-membered monocyclic aromatic heterocyclic rings each containing a ring heteroatom selected from the group consisting of nitrogen, oxygen and sulfur; R1 is H, amino or the like; R2 is a halogen atom, alkyl or the like; and n is 0, 1 or 2). COPYRIGHT: (C)2013,JPOandINPIT