1426550-76-6

Basic information

• Product Name: 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide
• Synonyms: 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide
• CAS NO: 1426550-76-6
• Molecular Weight: 728.929
• Mol File: 1426550-76-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide(1426550-76-6)
• EPA Substance Registry System: 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide(1426550-76-6)

Safety Data

• Hazardous Substances Data: 1426550-76-6(Hazardous Substances Data)

Upstream product

• 1426550-59-5 2,3,4,6-tetra-O-benzyl-1-O-tert-butyldiphenylsilyl-L-iditol 
• 127656-51-3 5-Azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucitol 
• 127656-45-5 5-Azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucose 
• 40652-40-2 N-(cyclohexen-1-yl)formamide 
• 591-80-0 pent-4-enoic acid 
• 1121-57-9 1-isocyanocyclohexene 
• 78136-16-0 2,3,4,6-tetra-O-benzyl-D-glucitol 
• 616215-36-2 (3R,4R,5S)-1,3,4,5-tetrakis(benzyloxy)-6-(tert-butyldiphenylsilyloxy)hexan-2-ol 

Downstream Products

• 1426550-77-7 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonic acid 
• 1426550-78-8 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 
• 1426550-80-2 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonic acid 
• 1426550-81-3 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonamide 

Relevant articles and documents

The development of an aza-C-glycoside library based on a tandem staudinger/aza-wittig/ugi three-component reaction

We report the tandem Staudinger/aza-Wittig/Ugi three-component reaction mediated synthesis of a 64-member compound library of aza-C-glycosides. The library is composed of four pyrrolidine and three piperidine scaffolds, onto which a number of functional groups is grafted to form seven sublibraries. Variation in the library is achieved by transformation of two pentoses and a hexose into the corresponding 4-azidopentanal and 5-azidohexanal derivatives as precursors for the Staudinger/aza-Wittig process. Further variation is achieved by using different isocyanides as well as protective- and functional-group manipulations on the fully protected Ugi-3CR intermediates. Preliminary biological evaluation of the compound library revealed several low micromolar inhibitors of human acid glucosylceramidase.