127656-45-5

Upstream product

• 127656-51-3 5-Azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucitol 
• 127656-44-4 5-Azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucose diethyldithioacetal 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 78136-16-0 2,3,4,6-tetra-O-benzyl-D-glucitol 
• 616215-36-2 (3R,4R,5S)-1,3,4,5-tetrakis(benzyloxy)-6-(tert-butyldiphenylsilyloxy)hexan-2-ol 
• 616215-37-3 Methanesulfonic acid (1R,2S,3R,4S)-2,3,4-tris-benzyloxy-1-benzyloxymethyl-5-(tert-butyl-diphenyl-silanyloxy)-pentyl ester 
• 127708-83-2 5-Azido-3,6-di-O-benzyl-5-deoxy-α/β-D-glucofuranose 
• 16958-26-2 1,2-O-isopropylidene-3,6-di-O-benzyl-5-azido-5-deoxy-α-D-glucofuranose 
• 1426550-59-5 2,3,4,6-tetra-O-benzyl-1-O-tert-butyldiphenylsilyl-L-iditol 

Downstream Products

• 127656-46-6 (E/Z)-5-Azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucose oxime 
• 1426550-81-3 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonamide 
• 1426550-80-2 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonic acid 
• 1426550-78-8 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 
• 1426550-77-7 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonic acid 
• 1426550-76-6 1-cyclohexenyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 
• 1426550-66-4 pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonamide 
• 1426550-65-3 1,1,3,3-tetramethylbutyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonamide 
• 1426550-64-2 5-(adamantan-1-yl-methoxy)pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-imino-D-glycero-D-idoheptonamide 
• 1426550-63-1 pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 
• 1426550-62-0 1,1,3,3-tetramethylbutyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 
• 1426550-61-9 5-(adamantan-1-yl-methoxy)pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-D-glycero-D-idoheptonamide 

Relevant academic research and scientific papers

The development of an aza-C-glycoside library based on a tandem staudinger/aza-wittig/ugi three-component reaction

We report the tandem Staudinger/aza-Wittig/Ugi three-component reaction mediated synthesis of a 64-member compound library of aza-C-glycosides. The library is composed of four pyrrolidine and three piperidine scaffolds, onto which a number of functional groups is grafted to form seven sublibraries. Variation in the library is achieved by transformation of two pentoses and a hexose into the corresponding 4-azidopentanal and 5-azidohexanal derivatives as precursors for the Staudinger/aza-Wittig process. Further variation is achieved by using different isocyanides as well as protective- and functional-group manipulations on the fully protected Ugi-3CR intermediates. Preliminary biological evaluation of the compound library revealed several low micromolar inhibitors of human acid glucosylceramidase.

Nitrogen inversion as a diastereomeric relay in azasugar synthesis: The first synthesis of adenophorine

A temperature-dependent relay of chirality is based on the inversion of the nitrogen lone pair in cyclic azasugars. Elimination from the conformation preferred at a given temperature leads to a cyclic imine, and in a subsequent nucleophilic attack the ste

The synthesis of protected 5-azido-5-deoxy-D-glucononitriles as precursors of glycosidase inhibitors

The successful syntheses of 5-azido-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucononitrile and 2,3,4,6-tetra-O-benzyl-5-deoxy-5-trifluoroacetamido-D-glucononitrile starting from D-glucose are described.Unsuccessful attempts were made to convert these two compoun