1426654-56-9

Upstream product

• 441715-92-0 6-fluoro-1-methyl-1H-indole 
• 611-73-4 Benzoylformic acid 
• 399-51-9 6-fluoro-1H-indole 
• 201230-82-2 carbon monoxide 
• 98-09-9 benzenesulfonyl chloride 
• 98-88-4 benzoyl chloride 

Relevant academic research and scientific papers

Visible light-induced carbonylation of indoles with arylsulfonyl chlorides and CO

A novel and simple strategy for the visible light-induced efficient synthesis of indol-3-yl aryl ketones from readily available arylsulfonyl chlorides and indoles with CO at room temperature was developed. This metal-free protocol has good functional group tolerance and avoids the use of transition-metal catalysts, additives, and alkaline or acidic reaction medium.

Synthetic method of indole-3-aromatic ketone derivative

The invention provides a novel method for an indole-3-aromatic ketone derivative. By using induction action of visible light, indole and aryl sulfonyl chloride and carbon monoxide are subjected to a reaction under normal temperature to generate indole-3-aromatic ketone, according to the novel synthetic method, the reaction mediums such as a transition-metal catalyst, an additive, acid and alkali are not required, the indole-3-aromatic ketone has good compatibility to a function group, the raw materials in the method have the advantages of simpleness and easy acquisition, and the method accords with a green chemistry scope.

AZA-PYRIDONE COMPOUNDS AND USES THEREOF

Disclosed herein are aza-pyridone compounds, pharmaceutical compositions that include one or more aza-pyridone compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection, with an aza-pyridone compound. Examples of an orthomyxovirus viral infection include an influenza infection.

Copper-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids

A novel and efficient Cu-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids for the synthesis of 3-acylindoles was developed. The Royal Society of Chemistry.