142687-66-9

Basic information

• Product Name: [(1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-4-(3-imidazol-1-yl-propylcarbamoyl)-5-methyl-hexyl]-carbamic acid tert-butyl ester
• Synonyms: [(1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-4-(3-imidazol-1-yl-propylcarbamoyl)-5-methyl-hexyl]-carbamic acid tert-butyl ester
• CAS NO: 142687-66-9
• Molecular Weight: 478.676
• Mol File: 142687-66-9.mol

Chemical Properties

• CAS DataBase Reference: [(1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-4-(3-imidazol-1-yl-propylcarbamoyl)-5-methyl-hexyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-4-(3-imidazol-1-yl-propylcarbamoyl)-5-methyl-hexyl]-carbamic acid tert-butyl ester(142687-66-9)
• EPA Substance Registry System: [(1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-4-(3-imidazol-1-yl-propylcarbamoyl)-5-methyl-hexyl]-carbamic acid tert-butyl ester(142687-66-9)

Safety Data

• Hazardous Substances Data: 142687-66-9(Hazardous Substances Data)

Upstream product

• 5036-48-6 3-(1H-imidazol-1-yl)propan-1-amine 
• 124032-36-6 (3S,5S)-5-[(1S)-1-(t-butoxycarbonyl)amino-2-cyclohexylethyl]-3-isopropyldihydrofuran-2(3H)-one 

Downstream Products

• 130316-96-0 (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethylamino]-hexanoylamino}-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid (3-imidazol-1-yl-propyl)-amide 

Relevant articles and documents

Nonpeptide renin inhibitors with good intraduodenal bioavailability and efficacy in dog

The aim of this study was the discovery of nonpeptide renin inhibitors with much improved oral absorption, bioavailability, and efficacy, for use as antihypertensive agents. Our prior efforts led to the identification of A- 74273 [1, R = 3-(4-morpholino)p