1426943-70-5

Basic information

• Product Name: ethyl 5-[(tert-butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)amino]pent-2-enoate
• Synonyms: ethyl 5-[(tert-butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)amino]pent-2-enoate
• CAS NO: 1426943-70-5
• Molecular Weight: 378.469
• Mol File: 1426943-70-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5-[(tert-butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)amino]pent-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-[(tert-butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)amino]pent-2-enoate(1426943-70-5)
• EPA Substance Registry System: ethyl 5-[(tert-butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)amino]pent-2-enoate(1426943-70-5)

Safety Data

• Hazardous Substances Data: 1426943-70-5(Hazardous Substances Data)

Upstream product

• 1426943-67-0 ethyl 5-[methyl(tert-butoxycarbonyl)amino]-3-oxopentanoate 
• 104-94-9 4-methoxy-aniline 
• 124072-61-3 N-t-butoxycarbonyl-N-methyl-β-alanine 
• 119740-95-3 methyl 3-(N-tert-butoxycarbonyl-N-methyl)-aminopropionate 

Downstream Products

• 41505-84-4 8-methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 

Relevant articles and documents

Constructions of tetrahydro-γ-carboline skeletons via intramolecular oxidative carbon-carbon bond formation of enamines

The synthetically and biologically important 4-methyl and 4-methoxy tetrahydro-γ-carboline compounds were readily synthesized in high yields from an aryl amine and a 5-amino-3-oxopentanoate derivative through a series of reactions of enamination, oxidative annulation, deprotection/lactamization and the final reduction reaction of the carbonyl group. The underpinning strategy involves the oxidative C(sp2)-C(sp2) bond formation realized by either Pd(OAc)2/Cu(OAc)2 or a hypervalent iodine reagent.