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1427166-96-8

1427166-96-8

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1427166-96-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1427166-96-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,7,1,6 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1427166-96:
(9*1)+(8*4)+(7*2)+(6*7)+(5*1)+(4*6)+(3*6)+(2*9)+(1*6)=168
168 % 10 = 8
So 1427166-96-8 is a valid CAS Registry Number.

1427166-96-8Downstream Products

1427166-96-8Relevant articles and documents

SAR development of lysine-based irreversible inhibitors of transglutaminase 2 for huntington's disease

Wityak, John,Prime, Michael E.,Brookfield, Frederick A.,Courtney, Stephen M.,Erfan, Sayeh,Johnsen, Siw,Johnson, Peter D.,Li, Marie,Marston, Richard W.,Reed, Laura,Vaidya, Darshan,Schaertl, Sabine,Pedret-Dunn, Anna,Beconi, Maria,MacDonald, Douglas,Mu?oz-Sanjuan, Ignacio,Dominguez, Celia

supporting information, p. 1024 - 1028 (2013/02/22)

We report a series of irreversible transglutaminase 2 inhibitors starting from a known lysine dipeptide bearing an acrylamide warhead. We established new SARs resulting in compounds demonstrating improved potency and better physical and calculated properties. Transglutaminase selectivity profiling and in vitro ADME properties of selected compounds are also reported.

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