1427688-91-2

Basic information

• Product Name: 5-bromo-4-isopropoxy-2-(4-tosylpiperazin-1-yl)pyrimidine
• Synonyms: 5-bromo-4-isopropoxy-2-(4-tosylpiperazin-1-yl)pyrimidine
• CAS NO: 1427688-91-2
• Molecular Weight: 455.376
• Mol File: 1427688-91-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-4-isopropoxy-2-(4-tosylpiperazin-1-yl)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-4-isopropoxy-2-(4-tosylpiperazin-1-yl)pyrimidine(1427688-91-2)
• EPA Substance Registry System: 5-bromo-4-isopropoxy-2-(4-tosylpiperazin-1-yl)pyrimidine(1427688-91-2)

Safety Data

• Hazardous Substances Data: 1427688-91-2(Hazardous Substances Data)

Upstream product

• 27106-51-0 1-tosylpiperazine 
• 1289215-25-3 C₇H₈BrClN₂O 

Downstream Products

• 1427688-92-3 4-isopropoxy-2-(4-tosylpiperazin-1-yl)-5-vinylpyrimidine 

Relevant articles and documents

Synthesis of pyrimidine-modified NHC ruthenium-alkylidene catalysts and their application in RCM, CM, em and ROMP reactions

A new type of N-heterocyclic carbene bearing ruthenium olefin metathesis catalyst was prepared through the incorporation of a chelated pyrimidinyl methylene subunit, in which electron-rich substituents were attached to stabilize the ruthenium complexes. These catalysts were successfully used in various types of olefin metathesis reactions, including ring-closing metathesis (RCM), cross-metathesis (CM), enyne metathesis (EM), and ring-opening metathesis polymerization (ROMP) reactions. The results therein showed that the presence of an electron-deficient pyrimidine structure greatly enhanced the new NHC ruthenium complexes' catalytic activities. New N-heterocyclic carbene bearing ruthenium olefin metathesis catalysts were synthesized and applied in various types of olefin metathesis reactions, including ring-closing metathesis, cross-metathesis, enyne metathesis, and ring-opening metathesis polymerization reactions. Copyright