142776-27-0Relevant articles and documents
Regioselective acylation of benzoselenazolinone
Galet,Vaccher,Bernier,Henichart,Lesieur
, p. 621 - 629 (1993)
Substitutions on benzoselenazolinone were performed by using successively (i) aliphatic or aromatic acids and (ii) acid chlorides in the presence of (i) polyphosphoric acid and (ii) aluminium chloride in dimethylformamide. Regioselective acylation at C6 position was demonstrated by 1H NMR using Nuclear Overhauser Effect.
Benzoselenazolinone Derivatives Designed To Be Glutathione Peroxidase Mimetics Feature Inhibition of Cyclooxygenase/5-Lipoxygenase Pathways and Anti-inflammatory Activity
Galet, Vincent,Bernier, Jean-Luc,Henichart, Jean-Piere,Lesieur, Daniel,Abadie, Claire,et al.
, p. 2903 - 2911 (2007/10/02)
Two series of compounds, substituted benzoselenazolinones and their opened analogs, diselenides, were prepared.The diselenides were designed according to the available SAR about glutathione peroxidase mimics and were expected to have activity.An initial s